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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML5
All Species:
26.97
Human Site:
T277
Identified Species:
98.89
UniProt:
Q05BV3
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05BV3
NP_899243.1
1969
219427
T277
T
V
I
D
L
R
E
T
D
Q
G
Y
K
G
L
Chimpanzee
Pan troglodytes
XP_510110
1978
220219
T277
T
V
I
D
L
R
E
T
D
Q
G
Y
K
G
L
Rhesus Macaque
Macaca mulatta
XP_001083969
1977
220271
T277
T
V
I
D
L
R
E
T
D
Q
G
Y
K
G
L
Dog
Lupus familis
XP_547946
1969
219445
T277
T
V
I
D
L
R
E
T
D
Q
G
Y
K
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQM8
1977
220088
T277
T
V
I
D
L
R
E
T
E
Q
G
Y
K
G
L
Rat
Rattus norvegicus
Q6ED65
1977
219789
T277
T
V
I
D
L
R
E
T
E
Q
G
Y
K
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509974
1966
218306
T277
T
K
I
D
L
R
E
T
E
Q
G
Y
K
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.9
96.8
N.A.
95.4
95.5
N.A.
73.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
99.2
98.7
N.A.
98.2
98.3
N.A.
86.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
100
0
0
0
0
58
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
100
0
43
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
100
0
0
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
0
0
0
0
0
0
0
0
0
0
100
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
100
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% T
% Val:
0
86
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _