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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTDSPL2 All Species: 11.52
Human Site: S131 Identified Species: 16.89
UniProt: Q05D32 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05D32 NP_057480.2 466 52999 S131 G K L E D N P S S G S P P R T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110308 466 52980 S131 G K L E D N P S S G S P P R T
Dog Lupus familis XP_544655 466 52994 S131 G K L E D N P S S G S P P R T
Cat Felis silvestris
Mouse Mus musculus Q8BG15 465 52794 C131 G K L E D N P C S G S P P R T
Rat Rattus norvegicus Q5XIK8 465 52764 C131 G K L E D N P C S G S P P R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511004 374 42210 I100 G E K P N K Q I S R V R R K G
Chicken Gallus gallus Q5F3Z7 466 52851 A131 G K L E D N P A T G S P P R T
Frog Xenopus laevis Q801R4 466 52941 T134 K L E D L P C T T S P P R T T
Zebra Danio Brachydanio rerio Q08BB5 469 52971 P131 L E V Q A E T P S S P P R T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRG7 243 28468
Honey Bee Apis mellifera XP_395439 486 56215 E131 T V S K V S E E S K E N W N V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788296 466 52589 S142 G T E T P A R S T L L G T I F
Poplar Tree Populus trichocarpa XP_002303804 244 28215
Maize Zea mays NP_001170732 254 29521
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196747 305 34829 P31 L D T S T V D P N C N L D S V
Baker's Yeast Sacchar. cerevisiae Q07949 397 44753 N123 D V E M T E V N N A G E E E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 99.3 N.A. 97.2 97 N.A. 71.4 93.7 82.6 73.5 N.A. 22.1 42.1 N.A. 46.7
Protein Similarity: 100 N.A. 100 99.5 N.A. 98.5 98.2 N.A. 75.5 97 90.1 82.7 N.A. 34.3 56.3 N.A. 61.5
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 13.3 86.6 13.3 20 N.A. 0 6.6 N.A. 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 33.3 100 33.3 40 N.A. 0 20 N.A. 20
Percent
Protein Identity: 29.1 30.4 N.A. 32.1 25.9 N.A.
Protein Similarity: 39.4 41.6 N.A. 45.9 45.4 N.A.
P-Site Identity: 0 0 N.A. 0 0 N.A.
P-Site Similarity: 0 0 N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 7 0 7 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 13 0 7 0 0 0 0 0 % C
% Asp: 7 7 0 7 38 0 7 0 0 0 0 0 7 0 0 % D
% Glu: 0 13 19 38 0 13 7 7 0 0 7 7 7 7 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 50 0 0 0 0 0 0 0 0 38 7 7 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 0 % I
% Lys: 7 38 7 7 0 7 0 0 0 7 0 0 0 7 0 % K
% Leu: 13 7 38 0 7 0 0 0 0 7 7 7 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 38 0 7 13 0 7 7 0 7 0 % N
% Pro: 0 0 0 7 7 7 38 13 0 0 13 50 38 0 0 % P
% Gln: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 7 0 7 19 38 0 % R
% Ser: 0 0 7 7 0 7 0 25 50 13 38 0 0 7 0 % S
% Thr: 7 7 7 7 13 0 7 7 19 0 0 0 7 13 50 % T
% Val: 0 13 7 0 7 7 7 0 0 0 7 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _