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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTDSPL2 All Species: 27.27
Human Site: S33 Identified Species: 40
UniProt: Q05D32 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05D32 NP_057480.2 466 52999 S33 K Y S E V D D S L P S G G E K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110308 466 52980 S33 K Y S E V D D S L P S G G E K
Dog Lupus familis XP_544655 466 52994 S33 K Y S E V D D S L P S G G E K
Cat Felis silvestris
Mouse Mus musculus Q8BG15 465 52794 S33 K Y S E V D D S L P S G G E K
Rat Rattus norvegicus Q5XIK8 465 52764 S33 K Y S E V D D S L P S G G E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511004 374 42210
Chicken Gallus gallus Q5F3Z7 466 52851 S33 K H S E V E E S L P V G G G K
Frog Xenopus laevis Q801R4 466 52941 S36 E E D E E E E S P L I E E D K
Zebra Danio Brachydanio rerio Q08BB5 469 52971 S33 K H S E V E H S L S T E D A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRG7 243 28468
Honey Bee Apis mellifera XP_395439 486 56215 V33 I Y N Y R V Q V R N I R K L P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788296 466 52589 E44 S R T I R N Q E K M P E G V T
Poplar Tree Populus trichocarpa XP_002303804 244 28215
Maize Zea mays NP_001170732 254 29521
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196747 305 34829
Baker's Yeast Sacchar. cerevisiae Q07949 397 44753 E25 H R Q R Q P P E T N H N R N R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 99.3 N.A. 97.2 97 N.A. 71.4 93.7 82.6 73.5 N.A. 22.1 42.1 N.A. 46.7
Protein Similarity: 100 N.A. 100 99.5 N.A. 98.5 98.2 N.A. 75.5 97 90.1 82.7 N.A. 34.3 56.3 N.A. 61.5
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 0 66.6 20 46.6 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 0 86.6 46.6 66.6 N.A. 0 13.3 N.A. 20
Percent
Protein Identity: 29.1 30.4 N.A. 32.1 25.9 N.A.
Protein Similarity: 39.4 41.6 N.A. 45.9 45.4 N.A.
P-Site Identity: 0 0 N.A. 0 0 N.A.
P-Site Similarity: 0 0 N.A. 0 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 32 32 0 0 0 0 0 7 7 0 % D
% Glu: 7 7 0 50 7 19 13 13 0 0 0 19 7 32 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 38 44 7 0 % G
% His: 7 13 0 0 0 0 7 0 0 0 7 0 0 0 0 % H
% Ile: 7 0 0 7 0 0 0 0 0 0 13 0 0 0 0 % I
% Lys: 44 0 0 0 0 0 0 0 7 0 0 0 7 0 50 % K
% Leu: 0 0 0 0 0 0 0 0 44 7 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 7 0 0 0 13 0 7 0 7 0 % N
% Pro: 0 0 0 0 0 7 7 0 7 38 7 0 0 0 7 % P
% Gln: 0 0 7 0 7 0 13 0 0 0 0 0 0 0 0 % Q
% Arg: 0 13 0 7 13 0 0 0 7 0 0 7 7 0 7 % R
% Ser: 7 0 44 0 0 0 0 50 0 7 32 0 0 0 0 % S
% Thr: 0 0 7 0 0 0 0 0 7 0 7 0 0 0 7 % T
% Val: 0 0 0 0 44 7 0 7 0 0 7 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 38 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _