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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTDSPL2 All Species: 25.15
Human Site: T234 Identified Species: 36.89
UniProt: Q05D32 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05D32 NP_057480.2 466 52999 T234 P P L T A P V T P D S G Y S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110308 466 52980 T234 P P L T A P V T P D S G Y S S
Dog Lupus familis XP_544655 466 52994 T234 P P L T A P V T P D S G Y S S
Cat Felis silvestris
Mouse Mus musculus Q8BG15 465 52794 T233 P P L T A P V T P E S G Y S S
Rat Rattus norvegicus Q5XIK8 465 52764 A233 P P L T A P V A P E S G Y S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511004 374 42210 T195 D E I T T S T T A S T N G A A
Chicken Gallus gallus Q5F3Z7 466 52851 S234 P P L T A P V S P D S G Y S S
Frog Xenopus laevis Q801R4 466 52941 S234 P P L T A P V S P E S G Y S S
Zebra Danio Brachydanio rerio Q08BB5 469 52971 N237 T A V G S N S N Y P D V P P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRG7 243 28468 V64 L V Q R K T L V L D L D E T L
Honey Bee Apis mellifera XP_395439 486 56215 E254 T K Y V G S E E I V E S C D M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788296 466 52589 M253 N D W P P C Q M Q Y A T Y E P
Poplar Tree Populus trichocarpa XP_002303804 244 28215 H64 D L D E T L V H S A L E P C N
Maize Zea mays NP_001170732 254 29521 D75 M T L V L D L D E T L V H S T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196747 305 34829 T126 D E T L V H S T L E P C G E V
Baker's Yeast Sacchar. cerevisiae Q07949 397 44753 P218 P G Y D T L L P P K L Q E F Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 99.3 N.A. 97.2 97 N.A. 71.4 93.7 82.6 73.5 N.A. 22.1 42.1 N.A. 46.7
Protein Similarity: 100 N.A. 100 99.5 N.A. 98.5 98.2 N.A. 75.5 97 90.1 82.7 N.A. 34.3 56.3 N.A. 61.5
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 86.6 N.A. 13.3 93.3 86.6 6.6 N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 93.3 N.A. 40 100 100 20 N.A. 20 0 N.A. 13.3
Percent
Protein Identity: 29.1 30.4 N.A. 32.1 25.9 N.A.
Protein Similarity: 39.4 41.6 N.A. 45.9 45.4 N.A.
P-Site Identity: 6.6 13.3 N.A. 6.6 13.3 N.A.
P-Site Similarity: 13.3 33.3 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 44 0 0 7 7 7 7 0 0 7 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 7 7 7 0 % C
% Asp: 19 7 7 7 0 7 0 7 0 32 7 7 0 7 0 % D
% Glu: 0 13 0 7 0 0 7 7 7 25 7 7 13 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 7 0 7 7 0 0 0 0 0 0 44 13 0 0 % G
% His: 0 0 0 0 0 7 0 7 0 0 0 0 7 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 7 0 0 7 0 0 0 0 7 0 0 0 0 0 % K
% Leu: 7 7 50 7 7 13 19 0 13 0 25 0 0 0 7 % L
% Met: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % M
% Asn: 7 0 0 0 0 7 0 7 0 0 0 7 0 0 7 % N
% Pro: 50 44 0 7 7 44 0 7 50 7 7 0 13 7 7 % P
% Gln: 0 0 7 0 0 0 7 0 7 0 0 7 0 0 7 % Q
% Arg: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 7 13 13 13 7 7 44 7 0 50 50 % S
% Thr: 13 7 7 50 19 7 7 38 0 7 7 7 0 7 7 % T
% Val: 0 7 7 13 7 0 50 7 0 7 0 13 0 0 7 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 0 0 0 0 0 7 7 0 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _