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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL2
All Species:
26.67
Human Site:
Y259
Identified Species:
39.11
UniProt:
Q05D32
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05D32
NP_057480.2
466
52999
Y259
W
E
V
F
D
P
Y
Y
F
I
K
H
V
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110308
466
52980
Y259
W
E
V
F
D
P
Y
Y
F
I
K
H
V
P
P
Dog
Lupus familis
XP_544655
466
52994
Y259
W
E
V
F
D
P
Y
Y
F
I
K
H
V
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG15
465
52794
Y258
W
E
V
F
D
P
Y
Y
F
I
K
H
V
P
P
Rat
Rattus norvegicus
Q5XIK8
465
52764
Y258
W
E
V
F
D
P
Y
Y
F
I
K
H
V
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511004
374
42210
E220
T
I
N
N
G
L
E
E
V
E
E
A
A
D
R
Chicken
Gallus gallus
Q5F3Z7
466
52851
Y259
W
E
V
F
D
P
Y
Y
F
I
K
H
V
P
P
Frog
Xenopus laevis
Q801R4
466
52941
F259
W
E
V
F
D
P
Y
F
F
I
K
H
V
P
P
Zebra Danio
Brachydanio rerio
Q08BB5
469
52971
F262
W
E
V
F
D
P
Y
F
F
I
K
H
V
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
P89
N
T
V
K
P
G
T
P
H
D
F
T
V
K
V
Honey Bee
Apis mellifera
XP_395439
486
56215
V279
W
E
P
F
D
P
Y
V
F
I
K
H
L
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788296
466
52589
Y278
W
E
T
F
D
P
Y
Y
F
I
K
Q
L
P
P
Poplar Tree
Populus trichocarpa
XP_002303804
244
28215
F89
N
L
Q
E
H
T
V
F
V
R
C
R
P
Y
L
Maize
Zea mays
NP_001170732
254
29521
R100
F
P
V
H
F
N
F
R
E
H
T
I
Y
V
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196747
305
34829
R151
E
E
H
M
V
Y
V
R
C
R
P
H
L
K
E
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
F243
E
T
L
V
H
S
S
F
K
Y
M
H
S
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
99.3
N.A.
97.2
97
N.A.
71.4
93.7
82.6
73.5
N.A.
22.1
42.1
N.A.
46.7
Protein Similarity:
100
N.A.
100
99.5
N.A.
98.5
98.2
N.A.
75.5
97
90.1
82.7
N.A.
34.3
56.3
N.A.
61.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
100
93.3
93.3
N.A.
13.3
80
N.A.
80
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
13.3
86.6
N.A.
86.6
Percent
Protein Identity:
29.1
30.4
N.A.
32.1
25.9
N.A.
Protein Similarity:
39.4
41.6
N.A.
45.9
45.4
N.A.
P-Site Identity:
0
6.6
N.A.
13.3
6.6
N.A.
P-Site Similarity:
6.6
20
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
63
0
0
0
0
7
0
0
0
7
7
% D
% Glu:
13
69
0
7
0
0
7
7
7
7
7
0
0
0
7
% E
% Phe:
7
0
0
63
7
0
7
25
63
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
7
7
13
0
0
0
7
7
0
69
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
63
0
7
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
7
0
63
0
0
13
0
% K
% Leu:
0
7
7
0
0
7
0
0
0
0
0
0
19
0
7
% L
% Met:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
13
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
0
7
63
0
7
0
0
7
0
7
63
63
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
0
13
0
7
0
0
13
% R
% Ser:
0
0
0
0
0
7
7
0
0
0
0
0
7
0
0
% S
% Thr:
7
13
7
0
0
7
7
0
0
0
7
7
0
0
0
% T
% Val:
0
0
63
7
7
0
13
7
13
0
0
0
57
7
7
% V
% Trp:
63
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
63
44
0
7
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _