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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL2
All Species:
19.09
Human Site:
Y27
Identified Species:
28
UniProt:
Q05D32
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05D32
NP_057480.2
466
52999
Y27
T
A
R
A
K
R
K
Y
S
E
V
D
D
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110308
466
52980
Y27
T
A
R
A
K
R
K
Y
S
E
V
D
D
S
L
Dog
Lupus familis
XP_544655
466
52994
Y27
T
A
R
A
K
R
K
Y
S
E
V
D
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG15
465
52794
Y27
T
A
R
A
K
R
K
Y
S
E
V
D
D
S
L
Rat
Rattus norvegicus
Q5XIK8
465
52764
Y27
T
A
R
A
K
R
K
Y
S
E
V
D
D
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511004
374
42210
Chicken
Gallus gallus
Q5F3Z7
466
52851
H27
A
Q
R
A
K
R
K
H
S
E
V
E
E
S
L
Frog
Xenopus laevis
Q801R4
466
52941
E30
C
K
R
K
H
S
E
E
D
E
E
E
E
S
P
Zebra Danio
Brachydanio rerio
Q08BB5
469
52971
H27
T
V
K
T
K
R
K
H
S
E
V
E
H
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
Honey Bee
Apis mellifera
XP_395439
486
56215
Y27
C
T
S
E
T
K
I
Y
N
Y
R
V
Q
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788296
466
52589
R38
N
N
N
N
N
N
S
R
T
I
R
N
Q
E
K
Poplar Tree
Populus trichocarpa
XP_002303804
244
28215
Maize
Zea mays
NP_001170732
254
29521
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196747
305
34829
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
R19
S
D
T
S
K
T
H
R
Q
R
Q
P
P
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
99.3
N.A.
97.2
97
N.A.
71.4
93.7
82.6
73.5
N.A.
22.1
42.1
N.A.
46.7
Protein Similarity:
100
N.A.
100
99.5
N.A.
98.5
98.2
N.A.
75.5
97
90.1
82.7
N.A.
34.3
56.3
N.A.
61.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
66.6
20
60
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
86.6
40
80
N.A.
0
20
N.A.
13.3
Percent
Protein Identity:
29.1
30.4
N.A.
32.1
25.9
N.A.
Protein Similarity:
39.4
41.6
N.A.
45.9
45.4
N.A.
P-Site Identity:
0
0
N.A.
0
6.6
N.A.
P-Site Similarity:
0
0
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
32
0
38
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
7
0
0
32
32
0
0
% D
% Glu:
0
0
0
7
0
0
7
7
0
50
7
19
13
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
7
13
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% I
% Lys:
0
7
7
7
50
7
44
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
44
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
7
7
7
7
0
0
7
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
7
% P
% Gln:
0
7
0
0
0
0
0
0
7
0
7
0
13
0
0
% Q
% Arg:
0
0
44
0
0
44
0
13
0
7
13
0
0
0
7
% R
% Ser:
7
0
7
7
0
7
7
0
44
0
0
0
0
50
0
% S
% Thr:
38
7
7
7
7
7
0
0
7
0
0
0
0
0
7
% T
% Val:
0
7
0
0
0
0
0
0
0
0
44
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
38
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _