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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITIH3 All Species: 26.36
Human Site: T238 Identified Species: 64.44
UniProt: Q06033 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06033 NP_002208.3 890 99849 T238 D Q Q R S C P T C T D S L L N
Chimpanzee Pan troglodytes XP_001172570 890 99706 T238 D Q Q R S C P T C T D S L L N
Rhesus Macaque Macaca mulatta XP_001085463 891 99603 T238 D Q Q R S C P T C T D S L L N
Dog Lupus familis XP_548489 897 100496 T244 D Q Q R S C P T C T D S L L N
Cat Felis silvestris
Mouse Mus musculus Q61704 889 99347 T238 D Q Q R S C P T C T D S L L N
Rat Rattus norvegicus Q63416 887 99079 T238 D Q Q R S C P T C T D S L L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508722 950 105792 V221 N F I V R Y D V R Q D A I D S
Chicken Gallus gallus XP_414253 886 99843 N237 D Q Q R T C E N C S Q S L L D
Frog Xenopus laevis NP_001088330 935 104948 T259 D E Q R Q C P T C S T T A V N
Zebra Danio Brachydanio rerio XP_693183 963 108893 C290 Q Q K K C S N C E A T L I D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 97.1 82 N.A. 84.9 83.9 N.A. 39.1 64.2 38 46.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 98.5 88.2 N.A. 92.5 91.9 N.A. 57.8 80 58.8 65.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 60 53.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 80 80 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 0 10 10 0 0 % A
% Cys: 0 0 0 0 10 80 0 10 80 0 0 0 0 0 0 % C
% Asp: 80 0 0 0 0 0 10 0 0 0 70 0 0 20 10 % D
% Glu: 0 10 0 0 0 0 10 0 10 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 20 0 0 % I
% Lys: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 10 70 70 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 10 0 0 0 0 0 0 70 % N
% Pro: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % P
% Gln: 10 80 80 0 10 0 0 0 0 10 10 0 0 0 0 % Q
% Arg: 0 0 0 80 10 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 60 10 0 0 0 20 0 70 0 0 10 % S
% Thr: 0 0 0 0 10 0 0 70 0 60 20 10 0 0 0 % T
% Val: 0 0 0 10 0 0 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _