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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITIH3
All Species:
34.85
Human Site:
Y451
Identified Species:
85.19
UniProt:
Q06033
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06033
NP_002208.3
890
99849
Y451
H
G
F
A
R
R
I
Y
E
D
S
D
A
D
L
Chimpanzee
Pan troglodytes
XP_001172570
890
99706
Y451
H
G
F
A
R
R
I
Y
E
D
S
D
A
D
L
Rhesus Macaque
Macaca mulatta
XP_001085463
891
99603
Y451
H
G
F
A
R
R
I
Y
E
D
S
D
A
D
L
Dog
Lupus familis
XP_548489
897
100496
Y457
H
G
L
A
R
R
I
Y
E
D
S
D
A
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61704
889
99347
Y451
H
G
L
A
R
R
I
Y
E
D
S
D
A
N
L
Rat
Rattus norvegicus
Q63416
887
99079
Y451
H
G
F
A
R
R
I
Y
E
D
S
D
A
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508722
950
105792
Y419
S
G
L
A
R
R
I
Y
E
D
S
D
A
A
L
Chicken
Gallus gallus
XP_414253
886
99843
Y450
K
G
L
A
R
R
I
Y
P
D
S
D
S
A
L
Frog
Xenopus laevis
NP_001088330
935
104948
Y472
H
G
M
A
Q
R
I
Y
G
N
Q
D
T
A
A
Zebra Danio
Brachydanio rerio
XP_693183
963
108893
Y500
D
G
L
A
R
R
V
Y
E
A
S
D
A
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.1
82
N.A.
84.9
83.9
N.A.
39.1
64.2
38
46.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
98.5
88.2
N.A.
92.5
91.9
N.A.
57.8
80
58.8
65.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
80
66.6
46.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
73.3
60
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
100
0
0
0
0
0
10
0
0
80
40
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
80
0
100
0
30
0
% D
% Glu:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% E
% Phe:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
90
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
90
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
20
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
90
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
90
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _