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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDSR
All Species:
12.12
Human Site:
S243
Identified Species:
26.67
UniProt:
Q06136
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06136
NP_002026.1
332
36187
S243
R
L
I
S
E
T
T
S
V
C
K
P
E
Q
V
Chimpanzee
Pan troglodytes
XP_001146068
298
32708
A214
Y
N
V
Y
I
T
V
A
Y
P
P
D
T
D
T
Rhesus Macaque
Macaca mulatta
XP_001089855
332
36200
S243
R
L
I
S
E
T
T
S
V
C
K
P
E
Q
V
Dog
Lupus familis
XP_852048
509
55662
S420
R
L
I
S
E
T
V
S
V
C
K
P
E
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6GV12
332
35937
A243
R
L
I
S
E
T
T
A
I
C
K
P
E
Q
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514447
278
30627
A197
L
C
R
P
E
Q
V
A
K
T
I
V
K
D
A
Chicken
Gallus gallus
NP_001026173
224
24518
M143
S
R
A
V
I
S
T
M
K
E
R
R
M
G
R
Frog
Xenopus laevis
Q0IH28
323
35135
L230
Y
I
K
T
N
L
S
L
N
A
V
T
G
D
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
V234
K
N
I
N
V
S
C
V
S
P
G
Y
I
R
T
Honey Bee
Apis mellifera
XP_392423
333
36866
S247
K
L
I
S
S
T
S
S
L
V
S
P
E
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790962
307
34092
G217
R
L
I
S
E
T
S
G
L
Y
A
A
Q
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.7
99.4
56.3
N.A.
92.7
N.A.
N.A.
68.9
58.4
26.2
N.A.
N.A.
26.8
45
N.A.
52.1
Protein Similarity:
100
89.7
99.6
61.2
N.A.
97.5
N.A.
N.A.
76.8
65.6
47.2
N.A.
N.A.
48.7
67.2
N.A.
70.1
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
6.6
53.3
N.A.
46.6
P-Site Similarity:
100
20
100
93.3
N.A.
100
N.A.
N.A.
20
20
20
N.A.
N.A.
33.3
73.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
28
0
10
10
10
0
0
10
% A
% Cys:
0
10
0
0
0
0
10
0
0
37
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
37
0
% D
% Glu:
0
0
0
0
55
0
0
0
0
10
0
0
46
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
10
0
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
64
0
19
0
0
0
10
0
10
0
10
0
0
% I
% Lys:
19
0
10
0
0
0
0
0
19
0
37
0
10
0
0
% K
% Leu:
10
55
0
0
0
10
0
10
19
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% M
% Asn:
0
19
0
10
10
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
19
10
46
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
10
37
0
% Q
% Arg:
46
10
10
0
0
0
0
0
0
0
10
10
0
10
10
% R
% Ser:
10
0
0
55
10
19
28
37
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
10
0
64
37
0
0
10
0
10
10
0
19
% T
% Val:
0
0
10
10
10
0
28
10
28
10
10
10
0
0
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
10
0
0
0
0
10
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _