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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDSR
All Species:
16.36
Human Site:
S265
Identified Species:
36
UniProt:
Q06136
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06136
NP_002026.1
332
36187
S265
A
I
Q
G
N
F
N
S
S
L
G
S
D
G
Y
Chimpanzee
Pan troglodytes
XP_001146068
298
32708
K231
F
A
E
E
N
R
T
K
P
L
E
T
R
L
I
Rhesus Macaque
Macaca mulatta
XP_001089855
332
36200
S265
A
I
Q
G
N
F
N
S
S
L
G
S
D
G
Y
Dog
Lupus familis
XP_852048
509
55662
S442
A
I
Q
G
N
F
N
S
S
I
G
S
D
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6GV12
332
35937
S265
A
I
Q
G
N
F
N
S
S
I
G
S
D
G
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514447
278
30627
C212
I
Q
G
N
F
S
S
C
V
G
S
D
G
Y
M
Chicken
Gallus gallus
NP_001026173
224
24518
A158
I
V
F
V
S
S
Q
A
G
Q
L
G
L
F
G
Frog
Xenopus laevis
Q0IH28
323
35135
N246
G
Y
G
V
M
D
K
N
T
A
D
G
R
T
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
K257
G
S
G
S
S
Y
G
K
V
D
E
T
T
A
K
Honey Bee
Apis mellifera
XP_392423
333
36866
G265
L
F
K
D
A
L
A
G
K
F
F
S
T
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790962
307
34092
S239
S
L
N
A
V
F
L
S
Y
V
G
M
D
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.7
99.4
56.3
N.A.
92.7
N.A.
N.A.
68.9
58.4
26.2
N.A.
N.A.
26.8
45
N.A.
52.1
Protein Similarity:
100
89.7
99.6
61.2
N.A.
97.5
N.A.
N.A.
76.8
65.6
47.2
N.A.
N.A.
48.7
67.2
N.A.
70.1
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
N.A.
N.A.
0
0
0
N.A.
N.A.
0
6.6
N.A.
40
P-Site Similarity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
6.6
20
13.3
N.A.
N.A.
20
13.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
0
10
10
0
10
10
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
10
10
10
46
0
0
% D
% Glu:
0
0
10
10
0
0
0
0
0
0
19
0
0
0
0
% E
% Phe:
10
10
10
0
10
46
0
0
0
10
10
0
0
10
0
% F
% Gly:
19
0
28
37
0
0
10
10
10
10
46
19
10
46
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
37
0
0
0
0
0
0
0
19
0
0
0
0
10
% I
% Lys:
0
0
10
0
0
0
10
19
10
0
0
0
0
0
10
% K
% Leu:
10
10
0
0
0
10
10
0
0
28
10
0
10
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
10
10
46
0
37
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
10
37
0
0
0
10
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
19
0
0
% R
% Ser:
10
10
0
10
19
19
10
46
37
0
10
46
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
10
0
0
19
19
10
0
% T
% Val:
0
10
0
19
10
0
0
0
19
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
10
0
0
0
0
10
46
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _