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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R3A All Species: 17.27
Human Site: S199 Identified Species: 31.67
UniProt: Q06190 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06190 NP_002709.2 1150 130278 S199 S L D T N L T S M F L Q N F S
Chimpanzee Pan troglodytes XP_001153482 1150 130149 S199 S L D T N L T S M F L Q N F S
Rhesus Macaque Macaca mulatta XP_001115107 1150 130076 S199 S L D T N L T S M F L Q N F S
Dog Lupus familis XP_542792 1152 130075 S199 S L D T N L T S V L L H N F S
Cat Felis silvestris
Mouse Mus musculus Q9Z176 491 55687
Rat Rattus norvegicus NP_001012202 1150 129888 M199 L D T S L T S M L F Q N L S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518335 657 71327
Chicken Gallus gallus XP_422556 1117 125703 S199 M N P M V P F S P H S F S E E
Frog Xenopus laevis NP_001082623 1127 126700 A200 Q N L N N M A A L Y L Q G L A
Zebra Danio Brachydanio rerio XP_694203 1163 130076 T205 Q N L N N V A T L Y L N S L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650842 888 97842
Honey Bee Apis mellifera XP_396366 1240 138144 S239 L T P S S A N S S S A N S T G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784322 739 85352
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.6 90.4 N.A. 27.8 85 N.A. 34 59.6 54 55.5 N.A. 32.6 30.7 N.A. 31.1
Protein Similarity: 100 99.7 98.8 94.6 N.A. 34.5 91 N.A. 43.1 73.3 68.7 70.8 N.A. 47.7 47.1 N.A. 45
P-Site Identity: 100 100 100 80 N.A. 0 6.6 N.A. 0 6.6 20 13.3 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 0 26.6 N.A. 0 13.3 53.3 53.3 N.A. 0 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 16 8 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 31 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 16 % E
% Phe: 0 0 0 0 0 0 8 0 0 31 0 8 0 31 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 16 31 16 0 8 31 0 0 24 8 47 0 8 16 0 % L
% Met: 8 0 0 8 0 8 0 8 24 0 0 0 0 0 0 % M
% Asn: 0 24 0 16 47 0 8 0 0 0 0 24 31 0 0 % N
% Pro: 0 0 16 0 0 8 0 0 8 0 0 0 0 0 0 % P
% Gln: 16 0 0 0 0 0 0 0 0 0 8 31 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 31 0 0 16 8 0 8 47 8 8 8 0 24 8 31 % S
% Thr: 0 8 8 31 0 8 31 8 0 0 0 0 0 8 8 % T
% Val: 0 0 0 0 8 8 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _