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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R3A
All Species:
23.64
Human Site:
S616
Identified Species:
43.33
UniProt:
Q06190
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06190
NP_002709.2
1150
130278
S616
K
S
S
R
G
S
L
S
Q
E
K
E
M
M
Q
Chimpanzee
Pan troglodytes
XP_001153482
1150
130149
S616
K
S
S
R
G
S
L
S
Q
E
K
E
M
M
Q
Rhesus Macaque
Macaca mulatta
XP_001115107
1150
130076
S616
K
S
S
R
G
S
L
S
Q
E
K
E
M
M
Q
Dog
Lupus familis
XP_542792
1152
130075
S615
K
S
G
R
G
S
L
S
Q
E
K
E
M
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z176
491
55687
Rat
Rattus norvegicus
NP_001012202
1150
129888
S615
K
S
S
R
G
S
L
S
Q
E
K
E
M
M
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518335
657
71327
F158
F
S
R
R
S
V
D
F
D
L
I
Y
G
Q
C
Chicken
Gallus gallus
XP_422556
1117
125703
E609
G
S
L
S
K
E
K
E
V
M
Q
I
L
Q
E
Frog
Xenopus laevis
NP_001082623
1127
126700
V619
K
I
L
Q
E
T
M
V
T
S
P
S
S
P
S
Zebra Danio
Brachydanio rerio
XP_694203
1163
130076
T639
G
A
G
R
G
T
Q
T
K
E
R
E
V
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650842
888
97842
D389
A
A
T
A
T
S
M
D
A
T
P
A
T
A
A
Honey Bee
Apis mellifera
XP_396366
1240
138144
T664
V
P
H
P
E
L
T
T
Q
Q
K
Q
H
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784322
739
85352
V240
R
Q
K
S
Q
Q
I
V
N
V
P
Q
F
Y
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
90.4
N.A.
27.8
85
N.A.
34
59.6
54
55.5
N.A.
32.6
30.7
N.A.
31.1
Protein Similarity:
100
99.7
98.8
94.6
N.A.
34.5
91
N.A.
43.1
73.3
68.7
70.8
N.A.
47.7
47.1
N.A.
45
P-Site Identity:
100
100
100
93.3
N.A.
0
100
N.A.
13.3
6.6
6.6
33.3
N.A.
6.6
13.3
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
0
100
N.A.
13.3
26.6
26.6
80
N.A.
26.6
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
8
0
0
0
0
8
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
16
8
0
8
0
47
0
47
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% F
% Gly:
16
0
16
0
47
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
8
8
0
8
0
% I
% Lys:
47
0
8
0
8
0
8
0
8
0
47
0
0
0
0
% K
% Leu:
0
0
16
0
0
8
39
0
0
8
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
16
0
0
8
0
0
39
47
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
24
0
0
8
0
% P
% Gln:
0
8
0
8
8
8
8
0
47
8
8
16
0
16
39
% Q
% Arg:
8
0
8
54
0
0
0
0
0
0
8
0
0
0
16
% R
% Ser:
0
54
31
16
8
47
0
39
0
8
0
8
8
0
8
% S
% Thr:
0
0
8
0
8
16
8
16
8
8
0
0
8
0
0
% T
% Val:
8
0
0
0
0
8
0
16
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _