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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAT All Species: 44.55
Human Site: S53 Identified Species: 75.38
UniProt: Q06203 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06203 NP_002694.3 517 57399 S53 E S A G I V T S D G S S V P T
Chimpanzee Pan troglodytes XP_001140991 517 57441 S53 E S A G I V T S D G S S V P T
Rhesus Macaque Macaca mulatta XP_001085606 517 57427 S53 E S A G I V T S D G S S V P T
Dog Lupus familis XP_854170 517 57161 S53 E S A G I V T S D G N S V P T
Cat Felis silvestris
Mouse Mus musculus NP_742158 517 57385 S53 E S A G I V T S D G S A V P K
Rat Rattus norvegicus P35433 517 57419 S53 E S A G I V T S D G S S V P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521120 482 53569 T41 G L V N H V F T E D N V K K L
Chicken Gallus gallus P28173 510 56239 S53 E S A G I V T S D G E S S Q A
Frog Xenopus laevis NP_001083491 508 55847 S53 E S A G I V T S D G S S V P T
Zebra Danio Brachydanio rerio NP_001076346 508 55199 S53 E S A G I V T S T G T N P P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27601 546 59501 S95 E S A G I A T S E G K C S K N
Honey Bee Apis mellifera XP_396074 525 57582 S77 E S A G I V T S E G V C S K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780199 520 56746 S76 E S A G I I T S Q G S S K N Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04046 510 56701 C40 D A A G I A T C G S R G R I Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.4 94.1 N.A. 93 93.4 N.A. 81.4 82.4 80.6 73.5 N.A. 56.7 59.4 N.A. 65.1
Protein Similarity: 100 100 100 98 N.A. 96.1 96.7 N.A. 87.6 89.9 90.1 84.3 N.A. 70.8 76.3 N.A. 79
P-Site Identity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. 6.6 73.3 100 73.3 N.A. 53.3 60 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 26.6 73.3 100 86.6 N.A. 60 73.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 93 0 0 15 0 0 0 0 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 15 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 58 8 0 0 0 0 0 % D
% Glu: 86 0 0 0 0 0 0 0 22 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 93 0 0 0 0 8 86 0 8 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 93 8 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 8 0 15 22 15 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 15 8 0 8 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 58 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % R
% Ser: 0 86 0 0 0 0 0 86 0 8 50 58 22 0 8 % S
% Thr: 0 0 0 0 0 0 93 8 8 0 8 0 0 0 43 % T
% Val: 0 0 8 0 0 79 0 0 0 0 8 8 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _