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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC9
All Species:
16.97
Human Site:
S380
Identified Species:
28.72
UniProt:
Q06265
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06265
NP_001029366.1
439
48949
S380
M
D
T
G
V
E
V
S
D
I
G
S
Q
D
A
Chimpanzee
Pan troglodytes
XP_001154164
439
48943
S380
M
D
T
G
V
E
V
S
D
I
G
S
Q
D
A
Rhesus Macaque
Macaca mulatta
XP_001101063
442
49364
C383
Q
T
G
V
Q
W
Y
C
N
L
H
L
P
D
A
Dog
Lupus familis
XP_533302
440
49215
S381
M
D
T
G
V
E
V
S
N
I
G
S
Q
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHI7
438
48918
S381
K
M
D
T
G
E
V
S
D
I
G
S
Q
G
A
Rat
Rattus norvegicus
Q4QR75
437
48863
S380
K
M
D
T
G
E
V
S
D
I
G
S
Q
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513016
439
49457
Q382
E
R
E
D
E
P
V
Q
S
K
V
K
K
D
A
Chicken
Gallus gallus
NP_001030000
440
49356
M382
T
E
T
E
D
T
S
M
M
N
E
A
K
D
D
Frog
Xenopus laevis
NP_001085439
431
48014
K374
P
V
V
E
I
Q
S
K
K
T
S
L
N
D
D
Zebra Danio
Brachydanio rerio
NP_001006077
393
44117
I339
V
A
T
G
T
A
Q
I
G
E
G
I
V
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624243
396
44894
S348
T
W
N
V
S
E
S
S
E
E
E
V
S
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788833
437
48874
T376
S
D
S
E
E
E
E
T
F
T
L
D
N
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191609
438
48277
V379
L
A
S
R
G
D
P
V
T
K
S
S
S
T
K
Baker's Yeast
Sacchar. cerevisiae
Q05636
305
33943
D257
K
A
G
G
L
P
M
D
A
L
T
L
M
K
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
92.9
95.9
N.A.
92.4
92.9
N.A.
82.4
78.4
72.4
66.9
N.A.
N.A.
33.2
N.A.
48.5
Protein Similarity:
100
99.7
94.3
98.1
N.A.
95.9
95.9
N.A.
90.4
87.9
83.8
79.5
N.A.
N.A.
55.8
N.A.
69
P-Site Identity:
100
100
13.3
93.3
N.A.
60
60
N.A.
20
13.3
6.6
20
N.A.
N.A.
20
N.A.
13.3
P-Site Similarity:
100
100
26.6
100
N.A.
60
60
N.A.
26.6
33.3
20
40
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.5
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.3
45.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
0
0
8
0
0
8
0
0
8
0
8
50
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
29
15
8
8
8
0
8
29
0
0
8
0
58
22
% D
% Glu:
8
8
8
22
15
50
8
0
8
15
15
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
15
36
22
0
0
0
8
0
43
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
36
0
8
0
0
8
% I
% Lys:
22
0
0
0
0
0
0
8
8
15
0
8
15
8
8
% K
% Leu:
8
0
0
0
8
0
0
0
0
15
8
22
0
0
0
% L
% Met:
22
15
0
0
0
0
8
8
8
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
15
8
0
0
15
8
0
% N
% Pro:
8
0
0
0
0
15
8
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
8
8
8
8
0
0
0
0
36
0
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
15
0
8
0
22
43
8
0
15
43
15
0
8
% S
% Thr:
15
8
36
15
8
8
0
8
8
15
8
0
0
8
0
% T
% Val:
8
8
8
15
22
0
43
8
0
0
8
8
8
0
0
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _