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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSME1
All Species:
18.79
Human Site:
T186
Identified Species:
45.93
UniProt:
Q06323
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06323
NP_006254.1
249
28723
T186
S
E
R
G
D
A
V
T
K
A
A
K
Q
P
H
Chimpanzee
Pan troglodytes
XP_001166832
242
27890
T179
S
E
R
G
D
A
V
T
K
A
A
K
Q
P
H
Rhesus Macaque
Macaca mulatta
XP_001104073
249
28689
T186
S
E
R
G
D
A
V
T
K
A
A
K
Q
P
H
Dog
Lupus familis
XP_537380
249
28673
T186
S
E
R
G
D
A
V
T
K
A
A
K
Q
P
H
Cat
Felis silvestris
Mouse
Mus musculus
P97371
249
28654
A186
S
E
R
G
D
A
V
A
K
A
A
K
Q
P
H
Rat
Rattus norvegicus
Q63797
249
28558
A186
S
E
R
G
D
A
V
A
K
A
A
K
Q
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3J5
254
29463
S191
I
T
R
A
K
L
V
S
K
I
A
K
Y
P
H
Frog
Xenopus laevis
NP_001087963
244
27835
A181
S
E
R
G
D
A
V
A
K
A
A
K
S
P
H
Zebra Danio
Brachydanio rerio
NP_571450
248
28194
A183
S
E
R
G
D
A
V
A
K
A
S
K
Q
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393883
245
27989
S182
I
S
R
G
K
I
V
S
K
V
A
K
Y
P
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
99.1
98.8
N.A.
94.7
95.1
N.A.
N.A.
41.3
60.2
59.4
N.A.
N.A.
39.3
N.A.
N.A.
Protein Similarity:
100
95.5
99.5
99.5
N.A.
98.3
97.9
N.A.
N.A.
65.7
76.7
79.5
N.A.
N.A.
57.8
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
46.6
86.6
86.6
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
53.3
86.6
93.3
N.A.
N.A.
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
80
0
40
0
80
90
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
90
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
20
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
20
0
0
0
100
0
0
100
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% Q
% Arg:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
80
10
0
0
0
0
0
20
0
0
10
0
10
0
0
% S
% Thr:
0
10
0
0
0
0
0
40
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
100
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _