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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBPJ All Species: 23.03
Human Site: S437 Identified Species: 46.06
UniProt: Q06330 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06330 NP_005340.2 500 55663 S437 R N D G I I Y S T S L T F T Y
Chimpanzee Pan troglodytes XP_001166260 474 52714 S411 R N D G I I Y S T S L T F T Y
Rhesus Macaque Macaca mulatta XP_001084065 486 54408 T424 N D G I I Y S T S L T F T Y T
Dog Lupus familis XP_536269 486 54423 T424 N D G I I Y S T S L T F T Y T
Cat Felis silvestris
Mouse Mus musculus P31266 526 58519 S463 R N D G V I Y S T S L T F T Y
Rat Rattus norvegicus NP_001100101 465 51936 T403 N D G I I Y S T S L T F T Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514177 654 72560 S591 R N D G I I Y S T S L T F T Y
Chicken Gallus gallus XP_420752 484 54192 T422 N D G I I Y S T S L T F T Y T
Frog Xenopus laevis Q91880 501 55845 S438 R N D G V I Y S T S L T F T Y
Zebra Danio Brachydanio rerio NP_001077020 491 54441 F429 I Y S T T L T F T Y T P E P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P28159 594 66906 A511 R N D G I I Y A T G L T F T Y
Honey Bee Apis mellifera XP_397309 506 57106 R444 Q V P V S L V R N D G I I Y A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 96 95.5 N.A. 93.1 92.1 N.A. 73.3 93.1 94 88.5 N.A. 63.6 74.6 N.A. N.A.
Protein Similarity: 100 94.4 96.5 96.1 N.A. 93.7 92.5 N.A. 74.4 94.4 95.6 91.8 N.A. 73 82.4 N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 93.3 6.6 N.A. 100 6.6 93.3 6.6 N.A. 86.6 0 N.A. N.A.
P-Site Similarity: 100 100 26.6 26.6 N.A. 100 26.6 N.A. 100 26.6 100 13.3 N.A. 93.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 50 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 34 50 0 0 % F
% Gly: 0 0 34 50 0 0 0 0 0 9 9 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 34 67 50 0 0 0 0 0 9 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 17 0 0 0 34 50 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 34 50 0 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 0 0 0 9 0 9 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 50 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 0 0 9 0 9 0 34 42 34 42 0 0 0 0 0 % S
% Thr: 0 0 0 9 9 0 9 34 59 0 42 50 34 50 34 % T
% Val: 0 9 0 9 17 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 34 50 0 0 9 0 0 0 42 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _