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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBPJ All Species: 15.45
Human Site: S466 Identified Species: 30.91
UniProt: Q06330 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06330 NP_005340.2 500 55663 S466 A I L R A N S S Q V P P N E S
Chimpanzee Pan troglodytes XP_001166260 474 52714 S440 A I L R A N S S Q V P P N E S
Rhesus Macaque Macaca mulatta XP_001084065 486 54408 Q453 I L R A N S S Q V P P N E S N
Dog Lupus familis XP_536269 486 54423 Q453 I L R A N S S Q V P P N E S N
Cat Felis silvestris
Mouse Mus musculus P31266 526 58519 S492 A I L R A N S S Q V P S N E S
Rat Rattus norvegicus NP_001100101 465 51936 Q432 I L R A N S S Q V P T N E S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514177 654 72560 S620 A I L R A N S S L M A S N E P
Chicken Gallus gallus XP_420752 484 54192 L451 I L R A N S S L M A S S E T N
Frog Xenopus laevis Q91880 501 55845 S467 A I L R A N S S L L A S N E P
Zebra Danio Brachydanio rerio NP_001077020 491 54441 I458 G S A S L L S I S G N S T G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P28159 594 66906 Q540 E D V M R A R Q N N N N N N I
Honey Bee Apis mellifera XP_397309 506 57106 E473 P H C P P A D E I M R A P R A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 96 95.5 N.A. 93.1 92.1 N.A. 73.3 93.1 94 88.5 N.A. 63.6 74.6 N.A. N.A.
Protein Similarity: 100 94.4 96.5 96.1 N.A. 93.7 92.5 N.A. 74.4 94.4 95.6 91.8 N.A. 73 82.4 N.A. N.A.
P-Site Identity: 100 100 13.3 13.3 N.A. 93.3 6.6 N.A. 66.6 6.6 66.6 6.6 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 33.3 33.3 N.A. 93.3 26.6 N.A. 73.3 26.6 73.3 6.6 N.A. 13.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 0 9 34 42 17 0 0 0 9 17 9 0 0 9 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 9 0 0 0 0 34 42 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 9 0 0 0 9 9 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 34 42 0 0 0 0 0 9 9 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 34 42 0 9 9 0 9 17 9 0 0 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 9 17 0 0 0 0 0 % M
% Asn: 0 0 0 0 34 42 0 0 9 9 17 34 50 9 34 % N
% Pro: 9 0 0 9 9 0 0 0 0 25 42 17 9 0 17 % P
% Gln: 0 0 0 0 0 0 0 34 25 0 0 0 0 0 0 % Q
% Arg: 0 0 34 42 9 0 9 0 0 0 9 0 0 9 0 % R
% Ser: 0 9 0 9 0 34 84 42 9 0 9 42 0 25 25 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 9 9 0 % T
% Val: 0 0 9 0 0 0 0 0 25 25 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _