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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2C All Species: 27.88
Human Site: S181 Identified Species: 51.11
UniProt: Q06413 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06413 NP_002388.2 473 51221 S181 H P S L Q R N S M S P G V T H
Chimpanzee Pan troglodytes XP_001139828 503 54271 L179 T L T D S S M L S P P Q T T L
Rhesus Macaque Macaca mulatta XP_001086412 483 52310 S199 H P S L Q R N S M S P G V T H
Dog Lupus familis XP_858441 472 51065 S180 H P S L Q R N S M S P G V T H
Cat Felis silvestris
Mouse Mus musculus Q8CFN5 474 51260 S181 H P S L Q R N S M S P G V T H
Rat Rattus norvegicus Q2MJT0 495 53235 L180 T L A E S S M L S P P P A T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510456 503 54885 S211 H P S L Q R N S M S P G V T H
Chicken Gallus gallus Q9W6U8 499 53650 N188 P Q T T L H R N V S P G A P Q
Frog Xenopus laevis Q03413 498 54053 T190 Q P S L Q R N T V S P G L P Q
Zebra Danio Brachydanio rerio NP_571387 465 49956 S180 H P S L Q R N S M S P G V T H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 S181 N I S P R P S S S E T D S G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 D168 R S G S N H S D C A R N S A D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.4 93.3 99.1 N.A. 98.7 56.5 N.A. 93 63.1 56.6 79.4 N.A. 32.4 N.A. N.A. N.A.
Protein Similarity: 100 74.3 94.8 99.3 N.A. 99.7 69.2 N.A. 94 74.1 70.4 88.5 N.A. 50 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 13.3 N.A. 100 20 60 100 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 20 N.A. 100 40 80 100 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 36.7 37.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 8 0 0 16 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 8 0 0 0 8 0 0 8 % D
% Glu: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 62 0 8 8 % G
% His: 47 0 0 0 0 16 0 0 0 0 0 0 0 0 47 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 16 0 54 8 0 0 16 0 0 0 0 8 0 16 % L
% Met: 0 0 0 0 0 0 16 0 47 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 54 8 0 0 0 8 0 0 0 % N
% Pro: 8 54 0 8 0 8 0 0 0 16 77 8 0 16 0 % P
% Gln: 8 8 0 0 54 0 0 0 0 0 0 8 0 0 16 % Q
% Arg: 8 0 0 0 8 54 8 0 0 0 8 0 0 0 0 % R
% Ser: 0 8 62 8 16 16 16 54 24 62 0 0 16 0 0 % S
% Thr: 16 0 16 8 0 0 0 8 0 0 8 0 8 62 0 % T
% Val: 0 0 0 0 0 0 0 0 16 0 0 0 47 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _