Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2C All Species: 15.45
Human Site: S263 Identified Species: 28.33
UniProt: Q06413 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06413 NP_002388.2 473 51221 S263 R V L I P P G S K N T M P S V
Chimpanzee Pan troglodytes XP_001139828 503 54271 L293 P L S E E E E L E L N T Q R I
Rhesus Macaque Macaca mulatta XP_001086412 483 52310 L273 M N N R K P D L R V L I P P G
Dog Lupus familis XP_858441 472 51065 S262 R V L I P P G S K N T M P S V
Cat Felis silvestris
Mouse Mus musculus Q8CFN5 474 51260 S263 R V L I P P G S K N T M P S V
Rat Rattus norvegicus Q2MJT0 495 53235 M285 P P S S K G M M P P L N A Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510456 503 54885 S293 R V L I P P G S K N T M P S V
Chicken Gallus gallus Q9W6U8 499 53650 E289 G M M P P L T E E D E L E L N
Frog Xenopus laevis Q03413 498 54053 G278 R V I T S Q G G K G L M H H L
Zebra Danio Brachydanio rerio NP_571387 465 49956 R254 L S R K P D L R V L I P P G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 S311 S S S G V M N S A D I M S L N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 S58 S G K L F E Y S S T G M K Q T
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 N243 F Y P S P Y E N L P K P S L P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.4 93.3 99.1 N.A. 98.7 56.5 N.A. 93 63.1 56.6 79.4 N.A. 32.4 N.A. N.A. N.A.
Protein Similarity: 100 74.3 94.8 99.3 N.A. 99.7 69.2 N.A. 94 74.1 70.4 88.5 N.A. 50 N.A. N.A. N.A.
P-Site Identity: 100 0 13.3 100 N.A. 100 0 N.A. 100 6.6 33.3 13.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 20 26.6 100 N.A. 100 0 N.A. 100 40 46.6 13.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 36.7 37.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 0 0 16 0 0 0 0 0 % D
% Glu: 0 0 0 8 8 16 16 8 16 0 8 0 8 0 0 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 8 0 8 39 8 0 8 8 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 0 8 31 0 0 0 0 0 0 16 8 0 0 8 % I
% Lys: 0 0 8 8 16 0 0 0 39 0 8 0 8 0 0 % K
% Leu: 8 8 31 8 0 8 8 16 8 16 24 8 0 24 8 % L
% Met: 8 8 8 0 0 8 8 8 0 0 0 54 0 0 0 % M
% Asn: 0 8 8 0 0 0 8 8 0 31 8 8 0 0 16 % N
% Pro: 16 8 8 8 54 39 0 0 8 16 0 16 47 8 8 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 8 16 0 % Q
% Arg: 39 0 8 8 0 0 0 8 8 0 0 0 0 8 8 % R
% Ser: 16 16 24 16 8 0 0 47 8 0 0 0 16 31 0 % S
% Thr: 0 0 0 8 0 0 8 0 0 8 31 8 0 0 8 % T
% Val: 0 39 0 0 8 0 0 0 8 8 0 0 0 0 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _