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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2C
All Species:
19.39
Human Site:
S375
Identified Species:
35.56
UniProt:
Q06413
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06413
NP_002388.2
473
51221
S375
A
C
T
S
T
H
L
S
Q
S
S
N
L
S
L
Chimpanzee
Pan troglodytes
XP_001139828
503
54271
E405
Q
N
I
N
I
K
S
E
P
I
S
P
P
R
D
Rhesus Macaque
Macaca mulatta
XP_001086412
483
52310
S385
A
C
T
S
T
H
L
S
Q
S
S
N
L
S
L
Dog
Lupus familis
XP_858441
472
51065
S374
A
C
T
S
T
H
L
S
Q
S
S
N
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFN5
474
51260
S375
A
C
T
S
T
H
L
S
Q
S
S
N
L
S
L
Rat
Rattus norvegicus
Q2MJT0
495
53235
E397
Q
N
I
N
I
K
T
E
P
I
S
P
P
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510456
503
54885
S405
A
C
T
S
T
H
V
S
Q
S
T
N
L
S
L
Chicken
Gallus gallus
Q9W6U8
499
53650
I401
N
T
N
Q
N
I
N
I
K
S
E
P
I
S
P
Frog
Xenopus laevis
Q03413
498
54053
V390
P
V
S
L
S
N
L
V
S
S
S
H
L
P
H
Zebra Danio
Brachydanio rerio
NP_571387
465
49956
L366
Q
L
C
Q
S
S
A
L
S
L
P
S
N
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
G423
G
P
S
G
Q
G
G
G
G
G
G
G
G
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
F170
Q
V
Q
E
L
R
S
F
L
P
S
F
T
H
Y
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
T355
S
P
A
M
Y
S
G
T
A
S
P
K
T
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
93.3
99.1
N.A.
98.7
56.5
N.A.
93
63.1
56.6
79.4
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
74.3
94.8
99.3
N.A.
99.7
69.2
N.A.
94
74.1
70.4
88.5
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
86.6
13.3
26.6
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
100
26.6
53.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
39
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
16
% D
% Glu:
0
0
0
8
0
0
0
16
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
8
0
8
16
8
8
8
8
8
8
0
0
% G
% His:
0
0
0
0
0
39
0
0
0
0
0
8
0
8
8
% H
% Ile:
0
0
16
0
16
8
0
8
0
16
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
16
0
0
8
0
0
8
0
0
0
% K
% Leu:
0
8
0
8
8
0
39
8
8
8
0
0
47
0
39
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
16
8
16
8
8
8
0
0
0
0
39
8
0
16
% N
% Pro:
8
16
0
0
0
0
0
0
16
8
16
24
16
8
8
% P
% Gln:
31
0
8
16
8
0
0
0
39
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
16
0
% R
% Ser:
8
0
16
39
16
16
16
39
16
62
62
8
0
54
0
% S
% Thr:
0
8
39
0
39
0
8
8
0
0
8
0
16
0
0
% T
% Val:
0
16
0
0
0
0
8
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _