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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2C
All Species:
31.52
Human Site:
S430
Identified Species:
57.78
UniProt:
Q06413
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06413
NP_002388.2
473
51221
S430
S
L
S
S
C
S
S
S
Y
D
G
S
D
R
E
Chimpanzee
Pan troglodytes
XP_001139828
503
54271
S460
S
L
S
S
S
S
S
S
Y
D
G
S
D
R
E
Rhesus Macaque
Macaca mulatta
XP_001086412
483
52310
S440
S
L
S
S
C
S
S
S
Y
D
G
S
D
R
E
Dog
Lupus familis
XP_858441
472
51065
S429
S
L
S
S
C
S
S
S
Y
D
G
S
D
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFN5
474
51260
S430
D
S
L
S
S
C
S
S
S
Y
D
G
S
D
R
Rat
Rattus norvegicus
Q2MJT0
495
53235
S452
S
L
S
S
S
S
S
S
Y
D
G
S
D
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510456
503
54885
S460
S
L
S
S
C
S
S
S
Y
D
G
S
D
R
E
Chicken
Gallus gallus
Q9W6U8
499
53650
S456
S
L
S
S
S
S
S
S
Y
D
G
S
D
R
E
Frog
Xenopus laevis
Q03413
498
54053
P445
H
E
A
T
G
R
S
P
V
D
S
L
S
S
N
Zebra Danio
Brachydanio rerio
NP_571387
465
49956
S421
S
L
S
S
C
G
S
S
Y
D
G
S
D
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
A478
Y
E
G
Y
P
Y
R
A
L
M
G
H
N
P
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
N225
E
A
H
D
R
R
T
N
E
G
E
R
E
S
P
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
F410
T
Y
V
N
N
K
T
F
F
L
K
P
P
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
93.3
99.1
N.A.
98.7
56.5
N.A.
93
63.1
56.6
79.4
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
74.3
94.8
99.3
N.A.
99.7
69.2
N.A.
94
74.1
70.4
88.5
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
20
93.3
N.A.
100
93.3
13.3
86.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
20
93.3
N.A.
100
93.3
26.6
93.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
39
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
70
8
0
62
8
8
% D
% Glu:
8
16
0
0
0
0
0
0
8
0
8
0
8
0
54
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
8
0
0
0
8
70
8
0
0
8
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
62
8
0
0
0
0
0
8
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
8
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
0
8
8
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
16
8
0
0
0
0
8
0
62
16
% R
% Ser:
62
8
62
70
31
54
77
70
8
0
8
62
16
16
0
% S
% Thr:
8
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
8
0
0
62
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _