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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2C
All Species:
19.7
Human Site:
S461
Identified Species:
36.11
UniProt:
Q06413
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06413
NP_002388.2
473
51221
S461
P
D
E
R
E
S
P
S
V
K
R
M
R
L
S
Chimpanzee
Pan troglodytes
XP_001139828
503
54271
P491
N
T
E
D
R
E
S
P
S
V
K
R
M
R
M
Rhesus Macaque
Macaca mulatta
XP_001086412
483
52310
S471
P
D
E
R
E
S
P
S
V
K
R
M
R
L
S
Dog
Lupus familis
XP_858441
472
51065
S460
P
D
E
R
E
S
P
S
V
K
R
M
R
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFN5
474
51260
P461
S
P
D
E
R
E
S
P
S
V
K
R
M
R
L
Rat
Rattus norvegicus
Q2MJT0
495
53235
P483
N
A
E
D
R
E
S
P
S
V
K
R
M
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510456
503
54885
S491
P
D
E
R
E
S
P
S
V
K
R
M
R
L
S
Chicken
Gallus gallus
Q9W6U8
499
53650
P487
N
S
E
D
R
E
S
P
S
V
K
R
M
R
M
Frog
Xenopus laevis
Q03413
498
54053
R476
T
S
S
L
G
L
L
R
P
S
G
D
T
E
S
Zebra Danio
Brachydanio rerio
NP_571387
465
49956
S452
E
N
E
R
Q
S
P
S
V
K
R
M
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
Q509
L
A
A
V
A
V
Q
Q
Q
Q
Q
Q
P
H
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
N256
G
D
Q
S
S
L
A
N
S
P
P
E
A
K
R
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
T441
P
S
S
V
A
S
S
T
L
K
S
T
S
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
93.3
99.1
N.A.
98.7
56.5
N.A.
93
63.1
56.6
79.4
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
74.3
94.8
99.3
N.A.
99.7
69.2
N.A.
94
74.1
70.4
88.5
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
0
6.6
N.A.
100
6.6
6.6
80
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
13.3
13.3
N.A.
100
13.3
6.6
93.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
16
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
8
24
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
0
62
8
31
31
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
47
31
0
0
8
0
% K
% Leu:
8
0
0
8
0
16
8
0
8
0
0
0
0
39
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
39
31
0
24
% M
% Asn:
24
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
39
8
0
0
0
0
39
31
8
8
8
0
8
0
0
% P
% Gln:
0
0
8
0
8
0
8
8
8
8
8
8
0
0
8
% Q
% Arg:
0
0
0
39
31
0
0
8
0
0
39
31
39
31
8
% R
% Ser:
8
24
16
8
8
47
39
39
39
8
8
0
8
8
47
% S
% Thr:
8
8
0
0
0
0
0
8
0
0
0
8
8
0
8
% T
% Val:
0
0
0
16
0
8
0
0
39
31
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _