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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2C
All Species:
17.27
Human Site:
Y408
Identified Species:
31.67
UniProt:
Q06413
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06413
NP_002388.2
473
51221
Y408
R
T
T
T
P
S
R
Y
P
Q
H
T
R
H
E
Chimpanzee
Pan troglodytes
XP_001139828
503
54271
P438
P
Q
P
Q
P
Q
P
P
Q
P
Q
P
R
Q
E
Rhesus Macaque
Macaca mulatta
XP_001086412
483
52310
Y418
R
T
T
T
P
S
R
Y
P
Q
H
T
R
H
E
Dog
Lupus familis
XP_858441
472
51065
Y407
R
T
T
T
P
S
R
Y
P
Q
H
T
R
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFN5
474
51260
Y408
R
T
T
T
P
S
R
Y
P
Q
H
T
T
R
H
Rat
Rattus norvegicus
Q2MJT0
495
53235
P430
P
P
P
Q
P
P
Q
P
Q
P
Q
P
R
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510456
503
54885
Y438
R
T
T
T
P
S
R
Y
P
Q
H
T
R
H
E
Chicken
Gallus gallus
Q9W6U8
499
53650
Q434
P
Q
P
P
Q
P
P
Q
Q
P
P
Q
R
Q
E
Frog
Xenopus laevis
Q03413
498
54053
R423
P
A
S
P
N
R
E
R
S
T
G
T
P
L
S
Zebra Danio
Brachydanio rerio
NP_571387
465
49956
Q399
P
G
L
Y
G
V
P
Q
Q
T
P
L
R
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
R456
H
L
G
M
P
N
S
R
P
S
S
T
G
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
Q203
H
D
S
K
C
S
L
Q
N
T
D
S
D
T
T
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
N388
S
K
F
L
G
F
K
N
N
D
M
D
D
L
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
93.3
99.1
N.A.
98.7
56.5
N.A.
93
63.1
56.6
79.4
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
74.3
94.8
99.3
N.A.
99.7
69.2
N.A.
94
74.1
70.4
88.5
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
100
N.A.
80
20
N.A.
100
13.3
6.6
6.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
80
26.6
N.A.
100
13.3
13.3
13.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
8
8
16
0
8
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
54
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
16
0
0
0
0
0
8
0
8
0
0
% G
% His:
16
0
0
0
0
0
0
0
0
0
39
0
0
39
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
8
8
0
0
8
0
0
0
0
8
0
16
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
8
16
0
0
0
0
0
0
% N
% Pro:
39
8
24
16
62
16
24
16
47
24
16
16
8
0
0
% P
% Gln:
0
16
0
16
8
8
8
24
31
39
16
8
0
31
0
% Q
% Arg:
39
0
0
0
0
8
39
16
0
0
0
0
62
8
0
% R
% Ser:
8
0
16
0
0
47
8
0
8
8
8
8
0
0
8
% S
% Thr:
0
39
39
39
0
0
0
0
0
24
0
54
8
8
8
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
39
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _