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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2C
All Species:
45.15
Human Site:
Y57
Identified Species:
82.78
UniProt:
Q06413
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06413
NP_002388.2
473
51221
Y57
S
T
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Chimpanzee
Pan troglodytes
XP_001139828
503
54271
Y57
S
S
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Rhesus Macaque
Macaca mulatta
XP_001086412
483
52310
Y57
S
T
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Dog
Lupus familis
XP_858441
472
51065
Y57
S
T
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFN5
474
51260
Y57
S
T
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Rat
Rattus norvegicus
Q2MJT0
495
53235
Y57
S
S
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510456
503
54885
Y87
S
T
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Chicken
Gallus gallus
Q9W6U8
499
53650
Y57
S
S
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Frog
Xenopus laevis
Q03413
498
54053
Y57
H
S
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Zebra Danio
Brachydanio rerio
NP_571387
465
49956
Y57
S
T
N
K
L
F
Q
Y
A
S
T
D
M
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
Y57
S
S
N
K
L
Y
Q
Y
A
S
T
D
M
D
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
I46
C
Q
V
D
I
A
V
I
I
L
G
S
N
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
93.3
99.1
N.A.
98.7
56.5
N.A.
93
63.1
56.6
79.4
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
74.3
94.8
99.3
N.A.
99.7
69.2
N.A.
94
74.1
70.4
88.5
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
93.3
N.A.
100
93.3
86.6
100
N.A.
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
100
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
85
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
85
0
85
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
77
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
77
% K
% Leu:
0
0
0
0
85
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
85
0
0
% M
% Asn:
0
0
85
0
0
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
85
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
77
39
0
0
0
0
0
0
0
85
0
8
0
0
0
% S
% Thr:
0
47
0
0
0
0
0
0
0
0
85
0
0
0
8
% T
% Val:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _