KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU5F1B
All Species:
22.12
Human Site:
Y291
Identified Species:
54.07
UniProt:
Q06416
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06416
NP_001153014.1
359
38570
Y291
G
K
R
S
S
S
D
Y
A
Q
R
E
D
F
E
Chimpanzee
Pan troglodytes
Q7YR49
360
38582
Y292
G
K
R
S
S
S
D
Y
A
Q
R
E
D
F
E
Rhesus Macaque
Macaca mulatta
Q5TM49
360
38511
Y292
G
K
R
S
S
S
D
Y
A
Q
R
E
D
F
E
Dog
Lupus familis
XP_538830
360
38329
Y292
G
K
R
S
S
S
D
Y
S
Q
R
E
D
F
E
Cat
Felis silvestris
Mouse
Mus musculus
P20263
352
38198
Y285
G
K
R
S
S
I
E
Y
S
Q
R
E
E
Y
E
Rat
Rattus norvegicus
P56225
335
36982
S267
A
G
W
P
T
N
D
S
S
Q
R
E
N
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P15143
739
75964
K429
W
F
C
N
R
R
Q
K
E
K
R
I
N
P
P
Frog
Xenopus laevis
B7ZQA9
445
49017
Y374
G
K
R
Q
V
Y
P
Y
I
R
E
N
G
G
E
Zebra Danio
Brachydanio rerio
Q90270
472
51486
F405
G
K
R
L
A
L
P
F
D
D
E
C
V
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16241
427
45909
C353
E
V
V
R
V
W
F
C
N
R
R
Q
K
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
94.4
87.5
N.A.
81
48.1
N.A.
N.A.
22.7
35.9
34.7
N.A.
33.7
N.A.
N.A.
N.A.
Protein Similarity:
100
96.3
95.8
91.6
N.A.
86.6
59.3
N.A.
N.A.
32
46.9
45.3
N.A.
44.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
66.6
26.6
N.A.
N.A.
6.6
33.3
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
53.3
N.A.
N.A.
26.6
40
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
30
0
0
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
0
10
10
0
0
40
0
0
% D
% Glu:
10
0
0
0
0
0
10
0
10
0
20
60
10
20
60
% E
% Phe:
0
10
0
0
0
0
10
10
0
0
0
0
0
40
0
% F
% Gly:
70
10
0
0
0
0
0
0
0
0
0
0
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
70
0
0
0
0
0
10
0
10
0
0
10
0
10
% K
% Leu:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
10
0
0
10
20
0
0
% N
% Pro:
0
0
0
10
0
0
20
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
10
0
0
10
0
0
60
0
10
0
0
0
% Q
% Arg:
0
0
70
10
10
10
0
0
0
20
80
0
0
0
0
% R
% Ser:
0
0
0
50
50
40
0
10
30
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
10
0
20
0
0
0
0
0
0
0
10
10
0
% V
% Trp:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
60
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _