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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX1T1
All Species:
37.27
Human Site:
Y440
Identified Species:
91.11
UniProt:
Q06455
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06455
NP_004340.1
604
67566
Y440
L
H
R
P
A
S
G
Y
V
P
E
E
I
W
K
Chimpanzee
Pan troglodytes
XP_528188
799
88187
Y635
L
H
R
P
A
S
G
Y
V
P
E
E
I
W
K
Rhesus Macaque
Macaca mulatta
XP_001090215
652
70879
Y480
L
P
R
T
L
T
G
Y
M
P
E
D
I
W
R
Dog
Lupus familis
XP_850414
604
67397
Y440
L
H
R
P
A
S
G
Y
V
P
E
E
I
W
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61909
577
64319
Y413
L
H
R
P
A
S
G
Y
V
P
E
E
I
W
K
Rat
Rattus norvegicus
NP_001102127
577
64303
Y413
L
H
R
P
A
S
G
Y
V
P
E
E
I
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505430
605
67678
Y441
L
H
R
P
A
S
G
Y
V
P
E
E
I
W
K
Chicken
Gallus gallus
Q5F3B1
591
64855
Y426
A
P
R
P
L
S
G
Y
M
P
E
E
I
W
R
Frog
Xenopus laevis
Q9IAB2
586
65036
Y422
G
S
R
T
G
A
G
Y
V
T
D
E
I
W
R
Zebra Danio
Brachydanio rerio
NP_001070244
588
65517
Y422
L
H
R
P
V
S
G
Y
V
P
E
E
I
W
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.9
66.2
99.1
N.A.
94.6
94.3
N.A.
97.3
74.1
60.4
87.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.9
77.3
99.1
N.A.
94.8
94.6
N.A.
98.6
82.6
74.1
92.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
100
N.A.
100
100
N.A.
100
66.6
46.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
100
N.A.
100
80
66.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
60
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
90
90
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
100
0
0
0
0
0
0
0
0
% G
% His:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% K
% Leu:
80
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
20
0
80
0
0
0
0
0
90
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
30
% R
% Ser:
0
10
0
0
0
80
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
20
0
10
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
80
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _