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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APLP2
All Species:
21.52
Human Site:
Y721
Identified Species:
67.62
UniProt:
Q06481
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06481
NP_001135748.1
763
86956
Y721
V
M
L
R
K
R
Q
Y
G
T
I
S
H
G
I
Chimpanzee
Pan troglodytes
Q5IS80
770
86953
Y728
V
M
L
K
K
K
Q
Y
T
S
I
H
H
G
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536530
763
86644
Y721
V
M
L
R
K
R
Q
Y
G
T
I
S
H
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q06335
695
78926
Y653
V
M
L
R
K
R
Q
Y
G
T
I
S
H
G
I
Rat
Rattus norvegicus
P15943
765
86864
Y723
V
M
L
R
K
R
Q
Y
G
T
I
S
H
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
O93279
737
82838
Y695
V
M
L
R
K
K
Q
Y
T
S
I
H
H
G
V
Fruit Fly
Dros. melanogaster
P14599
887
98314
G846
S
R
S
P
H
A
Q
G
F
I
E
V
D
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10651
686
79416
R645
A
F
A
I
T
N
A
R
R
R
R
A
M
R
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.3
N.A.
94.6
N.A.
83
92.9
N.A.
N.A.
N.A.
N.A.
N.A.
47.5
26.4
N.A.
24.3
N.A.
Protein Similarity:
100
66.8
N.A.
97.1
N.A.
87.5
95.9
N.A.
N.A.
N.A.
N.A.
N.A.
64.2
43.8
N.A.
44.5
N.A.
P-Site Identity:
100
60
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
6.6
N.A.
0
N.A.
P-Site Similarity:
100
86.6
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
0
0
13
13
0
0
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% E
% Phe:
0
13
0
0
0
0
0
0
13
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
50
0
0
0
0
75
13
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
25
75
0
0
% H
% Ile:
0
0
0
13
0
0
0
0
0
13
75
0
0
0
50
% I
% Lys:
0
0
0
13
75
25
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
75
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
13
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
88
0
0
0
0
0
0
13
0
% Q
% Arg:
0
13
0
63
0
50
0
13
13
13
13
0
0
13
0
% R
% Ser:
13
0
13
0
0
0
0
0
0
25
0
50
0
0
0
% S
% Thr:
0
0
0
0
13
0
0
0
25
50
0
0
0
0
0
% T
% Val:
75
0
0
0
0
0
0
0
0
0
0
13
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _