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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GABPA All Species: 22.42
Human Site: S242 Identified Species: 49.33
UniProt: Q06546 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06546 NP_002031.2 454 51295 S242 P R G E I L W S H L E L L R K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104750 454 51303 S242 P R G E I L W S H L E L L R K
Dog Lupus familis XP_535570 454 51331 S242 P R G E I L W S H L E L L R K
Cat Felis silvestris
Mouse Mus musculus Q00422 454 51345 S242 P R G E I L W S H L E L L R K
Rat Rattus norvegicus P41156 441 50404 S242 N M C M G R A S R G K L G G Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521370 101 11349
Chicken Gallus gallus Q90837 478 53895 F229 R N T G G A T F I F P N T S V
Frog Xenopus laevis P41157 453 50997 G246 T K S P P M G G T Q N V N K S
Zebra Danio Brachydanio rerio NP_571662 455 51026 S236 P S G E I L W S H L E L L R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q04688 464 52626 T260 D P G N I F W T H L Q L L K E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178496 566 64979 K80 E F C E R F Q K E S E D L F W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 99.1 N.A. 96 25.1 N.A. 22.2 23.4 25.1 74.7 N.A. 38.1 N.A. N.A. 35.8
Protein Similarity: 100 N.A. 99.7 99.5 N.A. 98 42.5 N.A. 22.2 40.3 44.4 83.7 N.A. 56.9 N.A. N.A. 50.8
P-Site Identity: 100 N.A. 100 100 N.A. 100 13.3 N.A. 0 0 0 93.3 N.A. 46.6 N.A. N.A. 20
P-Site Similarity: 100 N.A. 100 100 N.A. 100 26.6 N.A. 0 0 26.6 93.3 N.A. 73.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 10 0 0 55 0 0 0 0 10 0 55 0 0 0 10 % E
% Phe: 0 10 0 0 0 19 0 10 0 10 0 0 0 10 0 % F
% Gly: 0 0 55 10 19 0 10 10 0 10 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 55 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 55 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 10 0 0 10 0 0 19 46 % K
% Leu: 0 0 0 0 0 46 0 0 0 55 0 64 64 0 0 % L
% Met: 0 10 0 10 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 10 0 0 0 0 0 0 10 10 10 0 0 % N
% Pro: 46 10 0 10 10 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 10 10 0 0 0 10 % Q
% Arg: 10 37 0 0 10 10 0 0 10 0 0 0 0 46 0 % R
% Ser: 0 10 10 0 0 0 0 55 0 10 0 0 0 10 10 % S
% Thr: 10 0 10 0 0 0 10 10 10 0 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 55 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _