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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GABPA
All Species:
21.21
Human Site:
S254
Identified Species:
46.67
UniProt:
Q06546
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06546
NP_002031.2
454
51295
S254
L
R
K
Y
V
L
A
S
Q
E
Q
Q
M
N
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104750
454
51303
S254
L
R
K
Y
V
L
A
S
Q
E
Q
Q
M
N
E
Dog
Lupus familis
XP_535570
454
51331
S254
L
R
K
Y
V
L
A
S
Q
E
Q
Q
M
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q00422
454
51345
S254
L
R
K
Y
V
L
A
S
Q
E
Q
Q
M
N
E
Rat
Rattus norvegicus
P41156
441
50404
S254
G
G
Q
D
S
F
E
S
I
E
S
Y
D
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521370
101
11349
Chicken
Gallus gallus
Q90837
478
53895
T241
T
S
V
Y
P
E
A
T
Q
R
I
T
T
R
P
Frog
Xenopus laevis
P41157
453
50997
R258
N
K
S
G
D
Q
Q
R
S
Q
P
D
P
Y
Q
Zebra Danio
Brachydanio rerio
NP_571662
455
51026
S248
L
R
K
Y
V
L
A
S
Q
D
Q
S
Q
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04688
464
52626
S272
L
K
E
C
N
F
V
S
V
V
H
K
R
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178496
566
64979
L335
L
F
W
T
H
L
E
L
L
K
R
T
V
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
99.1
N.A.
96
25.1
N.A.
22.2
23.4
25.1
74.7
N.A.
38.1
N.A.
N.A.
35.8
Protein Similarity:
100
N.A.
99.7
99.5
N.A.
98
42.5
N.A.
22.2
40.3
44.4
83.7
N.A.
56.9
N.A.
N.A.
50.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
0
20
0
66.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
26.6
N.A.
0
26.6
20
73.3
N.A.
40
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
55
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
10
10
0
0
0
0
10
0
10
10
0
0
% D
% Glu:
0
0
10
0
0
10
19
0
0
46
0
0
0
10
46
% E
% Phe:
0
10
0
0
0
19
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
19
46
0
0
0
0
0
0
10
0
10
0
0
0
% K
% Leu:
64
0
0
0
0
55
0
10
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
0
0
0
37
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
10
0
10
10
10
% P
% Gln:
0
0
10
0
0
10
10
0
55
10
46
37
10
0
19
% Q
% Arg:
0
46
0
0
0
0
0
10
0
10
10
0
10
10
0
% R
% Ser:
0
10
10
0
10
0
0
64
10
0
10
10
0
10
0
% S
% Thr:
10
0
0
10
0
0
0
10
0
0
0
19
10
0
0
% T
% Val:
0
0
10
0
46
0
10
0
10
10
0
0
10
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
55
0
0
0
0
0
0
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _