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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FMR1 All Species: 31.21
Human Site: T492 Identified Species: 68.67
UniProt: Q06787 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06787 NP_002015.1 632 71174 T492 G P G Y T S G T N S E A S N A
Chimpanzee Pan troglodytes XP_521294 920 101999 T780 G P G Y T S G T N S E A S N A
Rhesus Macaque Macaca mulatta XP_001087617 632 71070 T492 G P G Y T S G T N S E A S N A
Dog Lupus familis XP_866618 632 71180 T492 G P G Y T S G T N S E A S N A
Cat Felis silvestris
Mouse Mus musculus P35922 614 68971 T491 G P G Y T S G T N S E A S N A
Rat Rattus norvegicus Q80WE1 593 66762 T470 G P G Y T S G T N S E A S N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512307 600 67493 T461 G P G Y A S G T N S E A S N A
Chicken Gallus gallus XP_420363 565 63830 T426 G P G Y A S G T N S E A S N A
Frog Xenopus laevis Q2KHP9 564 63840 W447 H R D E L S D W S L A P A E D
Zebra Danio Brachydanio rerio NP_694495 569 63888 E445 T E S D H R D E L S D W S L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NFU0 684 76057 R551 E G S S R R R R R Q K N N N G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.2 94.4 97.4 N.A. 94.1 91.4 N.A. 86.3 82.7 78.3 66.4 N.A. 30.9 N.A. N.A. N.A.
Protein Similarity: 100 68.6 96.3 99 N.A. 95.4 92.7 N.A. 90.8 86.5 82.9 77 N.A. 48.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 6.6 20 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 20 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 0 0 0 0 10 73 10 0 82 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 19 0 0 0 10 0 0 0 10 % D
% Glu: 10 10 0 10 0 0 0 10 0 0 73 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 73 10 73 0 0 0 73 0 0 0 0 0 0 0 10 % G
% His: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 10 10 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 73 0 0 10 10 82 0 % N
% Pro: 0 73 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 10 0 0 10 19 10 10 10 0 0 0 0 0 0 % R
% Ser: 0 0 19 10 0 82 0 0 10 82 0 0 82 0 0 % S
% Thr: 10 0 0 0 55 0 0 73 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 73 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _