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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FMR1
All Species:
30
Human Site:
T594
Identified Species:
66
UniProt:
Q06787
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06787
NP_002015.1
632
71174
T594
E
R
S
V
H
T
K
T
L
Q
N
T
S
S
E
Chimpanzee
Pan troglodytes
XP_521294
920
101999
T882
E
R
S
V
H
T
K
T
L
Q
N
T
S
S
E
Rhesus Macaque
Macaca mulatta
XP_001087617
632
71070
T594
E
R
S
V
H
T
K
T
L
Q
N
T
S
S
E
Dog
Lupus familis
XP_866618
632
71180
T594
E
R
S
V
H
T
K
T
L
Q
N
T
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P35922
614
68971
S576
K
G
R
T
A
D
G
S
L
Q
S
A
S
S
E
Rat
Rattus norvegicus
Q80WE1
593
66762
S555
K
G
R
T
T
D
G
S
L
Q
S
T
S
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512307
600
67493
T562
E
R
S
V
H
T
K
T
L
Q
N
T
S
S
E
Chicken
Gallus gallus
XP_420363
565
63830
T527
E
R
S
V
H
T
K
T
L
Q
N
T
S
S
E
Frog
Xenopus laevis
Q2KHP9
564
63840
S531
T
K
T
L
Q
N
A
S
V
E
G
S
R
L
R
Zebra Danio
Brachydanio rerio
NP_694495
569
63888
R529
E
R
S
I
H
T
S
R
S
S
Q
A
M
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFU0
684
76057
Q646
Q
Q
Q
A
A
Q
Q
Q
Q
P
K
P
R
R
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
94.4
97.4
N.A.
94.1
91.4
N.A.
86.3
82.7
78.3
66.4
N.A.
30.9
N.A.
N.A.
N.A.
Protein Similarity:
100
68.6
96.3
99
N.A.
95.4
92.7
N.A.
90.8
86.5
82.9
77
N.A.
48.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
33.3
40
N.A.
100
100
0
33.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
53.3
60
N.A.
100
100
46.6
46.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
19
0
10
0
0
0
0
19
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% D
% Glu:
64
0
0
0
0
0
0
0
0
10
0
0
0
0
73
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
0
0
0
19
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
10
0
0
0
0
55
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
73
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
55
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
10
10
10
0
10
10
10
10
10
73
10
0
0
0
0
% Q
% Arg:
0
64
19
0
0
0
0
10
0
0
0
0
19
10
10
% R
% Ser:
0
0
64
0
0
0
10
28
10
10
19
10
73
73
0
% S
% Thr:
10
0
10
19
10
64
0
55
0
0
0
64
0
0
0
% T
% Val:
0
0
0
55
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _