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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGR3
All Species:
14.55
Human Site:
S40
Identified Species:
35.56
UniProt:
Q06889
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06889
NP_004421.2
387
42613
S40
L
N
L
F
S
G
S
S
D
S
V
V
H
Y
N
Chimpanzee
Pan troglodytes
XP_519651
349
38459
K25
D
I
G
L
T
N
E
K
P
N
P
E
L
S
Y
Rhesus Macaque
Macaca mulatta
XP_001092603
475
50169
G44
I
F
P
N
A
E
L
G
G
P
F
D
Q
M
N
Dog
Lupus familis
XP_543247
471
51963
S124
L
N
L
F
S
G
S
S
D
S
V
A
H
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
P43300
387
42617
S40
L
N
L
F
S
G
S
S
D
S
V
A
H
Y
N
Rat
Rattus norvegicus
P43301
387
42588
S40
L
N
L
F
S
G
S
S
D
S
V
A
H
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509408
291
31482
Chicken
Gallus gallus
Frog
Xenopus laevis
Q08427
421
46362
P40
P
A
S
V
T
I
F
P
N
V
D
L
G
G
P
Zebra Danio
Brachydanio rerio
Q05159
412
45134
G56
E
Q
I
N
A
G
D
G
L
I
N
G
D
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13360
604
62491
S133
N
G
A
G
G
G
S
S
G
N
H
G
Y
W
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
46.7
81.7
N.A.
98.9
98.7
N.A.
62.5
N.A.
43.9
50.4
N.A.
21.5
N.A.
N.A.
N.A.
Protein Similarity:
100
88.6
59.5
81.7
N.A.
99.2
99.2
N.A.
66.9
N.A.
59.8
66.2
N.A.
34.4
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
93.3
N.A.
93.3
86.6
N.A.
0
N.A.
0
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
20
93.3
N.A.
93.3
86.6
N.A.
0
N.A.
20
26.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
20
0
0
0
0
0
0
30
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
40
0
10
10
10
0
0
% D
% Glu:
10
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% E
% Phe:
0
10
0
40
0
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
10
10
10
60
0
20
20
0
0
20
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
40
0
0
% H
% Ile:
10
10
10
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
40
0
40
10
0
0
10
0
10
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% M
% Asn:
10
40
0
20
0
10
0
0
10
20
10
0
0
0
40
% N
% Pro:
10
0
10
0
0
0
0
10
10
10
10
0
0
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
40
0
50
50
0
40
0
0
0
10
20
% S
% Thr:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
10
0
0
0
0
0
10
40
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
40
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _