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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOX4
All Species:
4.55
Human Site:
S174
Identified Species:
11.11
UniProt:
Q06945
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06945
NP_003098.1
474
47263
S174
G
G
G
G
G
G
G
S
S
N
A
G
G
G
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098923
475
47331
S174
G
G
G
G
G
G
G
S
S
N
A
G
G
G
G
Dog
Lupus familis
XP_542944
321
34466
R42
T
P
S
G
H
I
K
R
P
M
N
A
F
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q06831
440
45149
G161
D
K
V
A
G
S
S
G
H
A
G
S
S
H
A
Rat
Rattus norvegicus
P0C1G9
395
42581
Y116
H
M
A
D
Y
P
D
Y
K
Y
R
P
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48435
396
43485
K117
M
A
D
Y
P
D
Y
K
Y
R
P
R
K
K
P
Frog
Xenopus laevis
Q91731
382
42714
L103
F
I
R
E
A
E
R
L
R
L
K
H
M
A
D
Zebra Danio
Brachydanio rerio
Q6RVD7
245
26782
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40656
669
72724
A302
A
I
N
G
T
T
T
A
G
R
K
S
K
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798084
367
40653
I88
P
D
M
H
N
A
E
I
S
K
R
L
G
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
39.8
N.A.
81.2
39.8
N.A.
N.A.
39
36.9
24.8
N.A.
20.6
N.A.
N.A.
31.6
Protein Similarity:
100
N.A.
99.7
46.8
N.A.
85
50.4
N.A.
N.A.
48.5
48.5
34.8
N.A.
35.2
N.A.
N.A.
42.6
P-Site Identity:
100
N.A.
100
6.6
N.A.
6.6
0
N.A.
N.A.
0
0
0
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
6.6
N.A.
6.6
0
N.A.
N.A.
0
0
0
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
10
10
0
10
0
10
20
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
10
0
10
10
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
10
0
10
10
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
20
20
20
40
30
20
20
10
10
0
10
20
30
20
20
% G
% His:
10
0
0
10
10
0
0
0
10
0
0
10
0
10
0
% H
% Ile:
0
20
0
0
0
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
10
10
10
20
0
20
20
10
% K
% Leu:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% L
% Met:
10
10
10
0
0
0
0
0
0
10
0
0
10
10
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
20
10
0
0
0
0
% N
% Pro:
10
10
0
0
10
10
0
0
10
0
10
10
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
10
10
10
20
20
10
10
20
10
% R
% Ser:
0
0
10
0
0
10
10
20
30
0
0
20
10
0
10
% S
% Thr:
10
0
0
0
10
10
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
10
10
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _