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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX4 All Species: 4.85
Human Site: S185 Identified Species: 11.85
UniProt: Q06945 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06945 NP_003098.1 474 47263 S185 G G G G G G A S G G G A N S K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098923 475 47331 S185 G G G G G G A S G G G A N S K
Dog Lupus familis XP_542944 321 34466 H53 A F M V W S Q H E R R K I M D
Cat Felis silvestris
Mouse Mus musculus Q06831 440 45149 A172 S S H A G G G A G G T S K P T
Rat Rattus norvegicus P0C1G9 395 42581 D127 P R K K P K T D P A A K P S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P48435 396 43485 P128 R K K P K M D P S A K P N A G
Frog Xenopus laevis Q91731 382 42714 Y114 H M A D Y P D Y K Y R P R K K
Zebra Danio Brachydanio rerio Q6RVD7 245 26782
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40656 669 72724 C313 S K R S T S T C Q S G S A S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798084 367 40653 L99 L G R R W K T L D E V A K S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 39.8 N.A. 81.2 39.8 N.A. N.A. 39 36.9 24.8 N.A. 20.6 N.A. N.A. 31.6
Protein Similarity: 100 N.A. 99.7 46.8 N.A. 85 50.4 N.A. N.A. 48.5 48.5 34.8 N.A. 35.2 N.A. N.A. 42.6
P-Site Identity: 100 N.A. 100 0 N.A. 26.6 6.6 N.A. N.A. 6.6 6.6 0 N.A. 20 N.A. N.A. 20
P-Site Similarity: 100 N.A. 100 0 N.A. 40 6.6 N.A. N.A. 13.3 6.6 0 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 0 0 20 10 0 20 10 30 10 10 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 20 10 10 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 30 20 20 30 30 10 0 30 30 30 0 0 0 10 % G
% His: 10 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 20 20 10 10 20 0 0 10 0 10 20 20 10 40 % K
% Leu: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % L
% Met: 0 10 10 0 0 10 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 30 0 0 % N
% Pro: 10 0 0 10 10 10 0 10 10 0 0 20 10 10 10 % P
% Gln: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % Q
% Arg: 10 10 20 10 0 0 0 0 0 10 20 0 10 0 0 % R
% Ser: 20 10 0 10 0 20 0 20 10 10 0 20 0 50 0 % S
% Thr: 0 0 0 0 10 0 30 0 0 0 10 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _