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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX4 All Species: 4.55
Human Site: S212 Identified Species: 11.11
UniProt: Q06945 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.44
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06945 NP_003098.1 474 47263 S212 G G A G G G V S K P H A K L I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098923 475 47331 S212 G G A G G G V S K P H A K L I
Dog Lupus familis XP_542944 321 34466 L80 R L G R R W Q L L Q D S E K I
Cat Felis silvestris
Mouse Mus musculus Q06831 440 45149 K199 S V G K P H A K L V P A G G S
Rat Rattus norvegicus P0C1G9 395 42581 K154 A A K G P G K K C A K L K A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P48435 396 43485 K155 K S A K S S G K K C S K L K A
Frog Xenopus laevis Q91731 382 42714 K141 A L T Q S P E K S P K S R S A
Zebra Danio Brachydanio rerio Q6RVD7 245 26782
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40656 669 72724 E340 P K Y E V K M E S A E Q L N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798084 367 40653 K126 M A Q Y P D Y K Y R P R K K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 39.8 N.A. 81.2 39.8 N.A. N.A. 39 36.9 24.8 N.A. 20.6 N.A. N.A. 31.6
Protein Similarity: 100 N.A. 99.7 46.8 N.A. 85 50.4 N.A. N.A. 48.5 48.5 34.8 N.A. 35.2 N.A. N.A. 42.6
P-Site Identity: 100 N.A. 100 6.6 N.A. 6.6 20 N.A. N.A. 13.3 6.6 0 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 100 20 N.A. 6.6 20 N.A. N.A. 13.3 20 0 N.A. 6.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 20 30 0 0 0 10 0 0 20 0 30 0 10 20 % A
% Cys: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 10 10 0 0 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 20 20 30 20 30 10 0 0 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 20 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 % I
% Lys: 10 10 10 20 0 10 10 50 30 0 20 10 40 30 0 % K
% Leu: 0 20 0 0 0 0 0 10 20 0 0 10 20 20 0 % L
% Met: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 10 0 0 0 30 10 0 0 0 30 20 0 0 0 10 % P
% Gln: 0 0 10 10 0 0 10 0 0 10 0 10 0 0 0 % Q
% Arg: 10 0 0 10 10 0 0 0 0 10 0 10 10 0 0 % R
% Ser: 10 10 0 0 20 10 0 20 20 0 10 20 0 10 30 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 10 0 20 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 0 10 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _