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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX4 All Species: 4.55
Human Site: S397 Identified Species: 11.11
UniProt: Q06945 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06945 NP_003098.1 474 47263 S397 S S S G S S S S D D E F E D D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098923 475 47331 S398 S S S G S S S S D D E F E D D
Dog Lupus familis XP_542944 321 34466 E245 E E A A A A E E G E E E T V A
Cat Felis silvestris
Mouse Mus musculus Q06831 440 45149 D364 S S G S S S S D D E F E D D L
Rat Rattus norvegicus P0C1G9 395 42581 D319 D A D D L M F D L S L N F S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P48435 396 43485 V320 R G G G R P P V R P Q P Q L L
Frog Xenopus laevis Q91731 382 42714 H306 T T S P A A S H E L L F D L S
Zebra Danio Brachydanio rerio Q6RVD7 245 26782 A169 S P P S F S Y A S P L G Y P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40656 669 72724 H560 Y G G P D A G H T T F Q A D D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798084 367 40653 G291 S V S S M S T G S S Y C A Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 39.8 N.A. 81.2 39.8 N.A. N.A. 39 36.9 24.8 N.A. 20.6 N.A. N.A. 31.6
Protein Similarity: 100 N.A. 99.7 46.8 N.A. 85 50.4 N.A. N.A. 48.5 48.5 34.8 N.A. 35.2 N.A. N.A. 42.6
P-Site Identity: 100 N.A. 100 6.6 N.A. 46.6 0 N.A. N.A. 6.6 20 13.3 N.A. 13.3 N.A. N.A. 20
P-Site Similarity: 100 N.A. 100 33.3 N.A. 60 6.6 N.A. N.A. 20 60 20 N.A. 20 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 20 30 0 10 0 0 0 0 20 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 0 10 10 10 0 0 20 30 20 0 0 20 40 30 % D
% Glu: 10 10 0 0 0 0 10 10 10 20 30 20 20 0 0 % E
% Phe: 0 0 0 0 10 0 10 0 0 0 20 30 10 0 0 % F
% Gly: 0 20 30 30 0 0 10 10 10 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 10 10 30 0 0 20 20 % L
% Met: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 10 20 0 10 10 0 0 20 0 10 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 10 10 10 20 % Q
% Arg: 10 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 50 30 40 30 30 50 40 20 20 20 0 0 0 10 10 % S
% Thr: 10 10 0 0 0 0 10 0 10 10 0 0 10 0 10 % T
% Val: 0 10 0 0 0 0 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 10 0 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _