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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX4 All Species: 12.73
Human Site: S425 Identified Species: 31.11
UniProt: Q06945 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06945 NP_003098.1 474 47263 S425 S L G S F S S S S A L D R D L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098923 475 47331 S426 S L G S F S S S S A L D R D L
Dog Lupus familis XP_542944 321 34466 C273 P G P A G L D C S A L D R D P
Cat Felis silvestris
Mouse Mus musculus Q06831 440 45149 S392 L G S F S S S S A L D R D L D
Rat Rattus norvegicus P0C1G9 395 42581 S347 A A G N L S L S L V D K D L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P48435 396 43485 S348 A A G N L S L S L V D K D L D
Frog Xenopus laevis Q91731 382 42714 S334 N S G N V S L S L V D K D L D
Zebra Danio Brachydanio rerio Q6RVD7 245 26782 P197 H T H T H S H P S P G N P G Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40656 669 72724 S588 S I L T T S N S P Q I G F N G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798084 367 40653 F319 S E F N N F N F G S V P D D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 39.8 N.A. 81.2 39.8 N.A. N.A. 39 36.9 24.8 N.A. 20.6 N.A. N.A. 31.6
Protein Similarity: 100 N.A. 99.7 46.8 N.A. 85 50.4 N.A. N.A. 48.5 48.5 34.8 N.A. 35.2 N.A. N.A. 42.6
P-Site Identity: 100 N.A. 100 40 N.A. 20 20 N.A. N.A. 20 20 13.3 N.A. 20 N.A. N.A. 20
P-Site Similarity: 100 N.A. 100 46.6 N.A. 26.6 33.3 N.A. N.A. 33.3 33.3 26.6 N.A. 53.3 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 20 0 10 0 0 0 0 10 30 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 40 30 50 40 40 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 10 20 10 0 10 0 0 0 0 10 0 0 % F
% Gly: 0 20 50 0 10 0 0 0 10 0 10 10 0 10 10 % G
% His: 10 0 10 0 10 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 % K
% Leu: 10 20 10 0 20 10 30 0 30 10 30 0 0 40 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 40 10 0 20 0 0 0 0 10 0 10 0 % N
% Pro: 10 0 10 0 0 0 0 10 10 10 0 10 10 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 30 0 0 % R
% Ser: 40 10 10 20 10 80 30 70 40 10 0 0 0 0 0 % S
% Thr: 0 10 0 20 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 30 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _