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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK18
All Species:
27.27
Human Site:
T141
Identified Species:
50
UniProt:
Q07002
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07002
NP_002587.2
472
54180
T141
I
G
F
G
K
L
E
T
Y
V
K
L
D
K
L
Chimpanzee
Pan troglodytes
XP_521035
762
83144
T430
I
G
F
G
K
L
E
T
Y
I
K
L
D
K
L
Rhesus Macaque
Macaca mulatta
XP_001100911
485
54881
T153
I
G
F
G
K
L
E
T
Y
I
K
L
D
K
L
Dog
Lupus familis
XP_539731
541
61618
T209
I
G
F
G
K
M
E
T
Y
I
K
L
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q04899
451
51829
T120
I
G
F
G
K
L
E
T
Y
V
K
L
D
K
L
Rat
Rattus norvegicus
O35832
451
51863
T120
I
G
F
G
K
L
E
T
Y
V
K
L
D
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510894
523
59528
T191
I
G
F
G
K
M
E
T
Y
I
K
L
E
K
L
Chicken
Gallus gallus
XP_001234978
430
49073
L125
R
S
K
L
T
E
N
L
V
A
L
K
E
I
R
Frog
Xenopus laevis
Q6DJM7
435
49211
G124
K
G
K
S
K
V
N
G
K
L
V
A
L
K
V
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
K118
A
L
K
V
I
H
M
K
T
E
E
G
I
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48609
294
33162
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
61.4
61.3
N.A.
87.7
88.1
N.A.
63.8
76.4
46.1
43.8
N.A.
34.1
N.A.
N.A.
N.A.
Protein Similarity:
100
53.1
75.2
73.9
N.A.
92.5
92.8
N.A.
77.4
81.9
61.6
57.4
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
80
N.A.
100
100
N.A.
80
0
20
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
40
6.6
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
33
N.A.
33.2
N.A.
N.A.
Protein Similarity:
N.A.
47
N.A.
47.8
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% D
% Glu:
0
0
0
0
0
8
54
0
0
8
8
0
24
0
0
% E
% Phe:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
62
0
54
0
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
54
0
0
0
8
0
0
0
0
31
0
0
8
8
0
% I
% Lys:
8
0
24
0
62
0
0
8
8
0
54
8
0
62
0
% K
% Leu:
0
8
0
8
0
39
0
8
0
8
8
54
8
0
54
% L
% Met:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
54
8
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
8
0
0
8
24
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _