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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK18 All Species: 27.58
Human Site: Y142 Identified Species: 50.56
UniProt: Q07002 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07002 NP_002587.2 472 54180 Y142 G F G K L E T Y V K L D K L G
Chimpanzee Pan troglodytes XP_521035 762 83144 Y431 G F G K L E T Y I K L D K L G
Rhesus Macaque Macaca mulatta XP_001100911 485 54881 Y154 G F G K L E T Y I K L D K L G
Dog Lupus familis XP_539731 541 61618 Y210 G F G K M E T Y I K L E K L G
Cat Felis silvestris
Mouse Mus musculus Q04899 451 51829 Y121 G F G K L E T Y V K L D K L G
Rat Rattus norvegicus O35832 451 51863 Y121 G F G K L E T Y V K L D K L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510894 523 59528 Y192 G F G K M E T Y I K L E K L G
Chicken Gallus gallus XP_001234978 430 49073 V126 S K L T E N L V A L K E I R L
Frog Xenopus laevis Q6DJM7 435 49211 K125 G K S K V N G K L V A L K V I
Zebra Danio Brachydanio rerio Q1RLU9 418 47889 T119 L K V I H M K T E E G I P F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48609 294 33162
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P23111 294 33816
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 61.4 61.3 N.A. 87.7 88.1 N.A. 63.8 76.4 46.1 43.8 N.A. 34.1 N.A. N.A. N.A.
Protein Similarity: 100 53.1 75.2 73.9 N.A. 92.5 92.8 N.A. 77.4 81.9 61.6 57.4 N.A. 44 N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 80 N.A. 100 100 N.A. 80 0 20 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 6.6 40 6.6 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 33 N.A. 33.2 N.A. N.A.
Protein Similarity: N.A. 47 N.A. 47.8 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 0 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 % D
% Glu: 0 0 0 0 8 54 0 0 8 8 0 24 0 0 0 % E
% Phe: 0 54 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 62 0 54 0 0 0 8 0 0 0 8 0 0 0 54 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 31 0 0 8 8 0 8 % I
% Lys: 0 24 0 62 0 0 8 8 0 54 8 0 62 0 0 % K
% Leu: 8 0 8 0 39 0 8 0 8 8 54 8 0 54 8 % L
% Met: 0 0 0 0 16 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 54 8 0 0 0 0 0 0 8 % T
% Val: 0 0 8 0 8 0 0 8 24 8 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 54 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _