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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK18
All Species:
24.85
Human Site:
Y227
Identified Species:
45.56
UniProt:
Q07002
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07002
NP_002587.2
472
54180
Y227
L
D
S
D
L
K
Q
Y
L
D
H
C
G
N
L
Chimpanzee
Pan troglodytes
XP_521035
762
83144
Y516
L
D
K
D
L
K
Q
Y
L
D
D
C
G
N
I
Rhesus Macaque
Macaca mulatta
XP_001100911
485
54881
Y239
L
D
K
D
L
K
Q
Y
L
D
D
C
G
N
I
Dog
Lupus familis
XP_539731
541
61618
Y295
L
D
K
D
L
K
Q
Y
M
D
D
C
G
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q04899
451
51829
Y206
L
D
S
D
L
K
Q
Y
L
D
H
C
G
N
L
Rat
Rattus norvegicus
O35832
451
51863
Y206
L
D
S
D
L
K
Q
Y
L
D
H
C
G
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510894
523
59528
Y277
L
D
K
D
L
K
Q
Y
M
D
D
C
G
N
I
Chicken
Gallus gallus
XP_001234978
430
49073
R207
I
F
M
F
Q
L
L
R
G
L
S
Y
C
H
E
Frog
Xenopus laevis
Q6DJM7
435
49211
L206
V
K
L
F
L
F
Q
L
L
R
G
L
S
Y
I
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
R199
G
L
S
Y
I
H
G
R
R
I
L
H
R
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48609
294
33162
K75
D
V
L
H
S
D
K
K
L
T
L
V
F
E
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
R75
D
V
V
H
S
E
K
R
I
Y
L
V
F
E
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
R75
D
V
V
H
S
E
K
R
L
Y
L
V
F
E
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
61.4
61.3
N.A.
87.7
88.1
N.A.
63.8
76.4
46.1
43.8
N.A.
34.1
N.A.
N.A.
N.A.
Protein Similarity:
100
53.1
75.2
73.9
N.A.
92.5
92.8
N.A.
77.4
81.9
61.6
57.4
N.A.
44
N.A.
N.A.
N.A.
P-Site Identity:
100
80
80
73.3
N.A.
100
100
N.A.
73.3
0
20
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
86.6
N.A.
100
100
N.A.
86.6
13.3
33.3
26.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
33
N.A.
33.2
N.A.
N.A.
Protein Similarity:
N.A.
47
N.A.
47.8
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
54
8
0
0
% C
% Asp:
24
54
0
54
0
8
0
0
0
54
31
0
0
8
0
% D
% Glu:
0
0
0
0
0
16
0
0
0
0
0
0
0
24
8
% E
% Phe:
0
8
0
16
0
8
0
0
0
0
0
0
24
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
8
0
8
0
54
0
0
% G
% His:
0
0
0
24
0
8
0
0
0
0
24
8
0
8
8
% H
% Ile:
8
0
0
0
8
0
0
0
8
8
0
0
0
0
39
% I
% Lys:
0
8
31
0
0
54
24
8
0
0
0
0
0
0
0
% K
% Leu:
54
8
16
0
62
8
8
8
62
8
31
8
0
0
31
% L
% Met:
0
0
8
0
0
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
62
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
31
8
8
0
0
8
0
0
% R
% Ser:
0
0
31
0
24
0
0
0
0
0
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
8
24
16
0
0
0
0
0
0
0
0
24
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
54
0
16
0
8
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _