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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGF
All Species:
31.52
Human Site:
S143
Identified Species:
57.78
UniProt:
Q07326
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07326
NP_002634.1
219
24890
S143
K
A
W
L
R
V
F
S
R
N
G
V
T
S
I
Chimpanzee
Pan troglodytes
XP_001147889
219
24970
S143
K
A
W
L
R
V
F
S
R
N
G
V
T
S
I
Rhesus Macaque
Macaca mulatta
XP_001113130
219
24899
S143
K
A
W
L
R
V
F
S
R
N
G
V
S
S
I
Dog
Lupus familis
XP_531809
219
25180
S143
K
A
W
L
R
V
F
S
R
N
G
V
T
S
I
Cat
Felis silvestris
Mouse
Mus musculus
O09101
219
24806
S143
K
A
W
L
R
V
F
S
R
N
G
V
T
S
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508401
403
43802
S198
H
A
W
Q
R
V
F
S
K
N
G
A
S
S
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088813
219
24617
S143
P
A
W
V
R
V
F
S
K
D
G
A
L
S
V
Zebra Danio
Brachydanio rerio
NP_991208
219
24392
S143
Q
A
W
I
R
V
F
S
R
D
G
A
M
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187877
166
17772
S101
L
A
Y
I
V
V
F
S
L
L
G
A
W
L
G
Poplar Tree
Populus trichocarpa
XP_002303863
230
25414
A154
T
Y
W
Q
R
I
F
A
Q
T
K
P
N
E
P
Maize
Zea mays
NP_001131399
218
23446
P146
S
H
S
I
Y
F
T
P
T
D
V
E
N
Y
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06636
219
25243
W138
A
P
L
M
D
L
L
W
E
T
W
L
L
S
L
Red Bread Mold
Neurospora crassa
Q871U9
272
28468
A203
G
V
D
S
A
A
W
A
A
V
G
G
F
R
A
Conservation
Percent
Protein Identity:
100
99.5
97.2
92.6
N.A.
87.6
N.A.
N.A.
28.5
N.A.
63
52.9
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
99.5
98.1
95.4
N.A.
92.2
N.A.
N.A.
38.2
N.A.
81.2
75.8
N.A.
N.A.
N.A.
N.A.
46.5
P-Site Identity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
66.6
N.A.
53.3
60
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
80
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
25.6
29.6
N.A.
N.A.
21.9
24.2
Protein Similarity:
44.7
49.3
N.A.
N.A.
38.3
38.9
P-Site Identity:
20
0
N.A.
N.A.
6.6
6.6
P-Site Similarity:
40
20
N.A.
N.A.
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
70
0
0
8
8
0
16
8
0
0
31
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
24
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
8
77
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
77
8
0
0
8
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
24
0
8
0
0
0
0
0
0
0
0
47
% I
% Lys:
39
0
0
0
0
0
0
0
16
0
8
0
0
0
0
% K
% Leu:
8
0
8
39
0
8
8
0
8
8
0
8
16
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
47
0
0
16
0
0
% N
% Pro:
8
8
0
0
0
0
0
8
0
0
0
8
0
0
8
% P
% Gln:
8
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
70
0
0
0
47
0
0
0
0
8
0
% R
% Ser:
8
0
8
8
0
0
0
70
0
0
0
0
16
70
0
% S
% Thr:
8
0
0
0
0
0
8
0
8
16
0
0
31
0
0
% T
% Val:
0
8
0
8
8
70
0
0
0
8
8
39
0
0
16
% V
% Trp:
0
0
70
0
0
0
8
8
0
0
8
0
8
0
0
% W
% Tyr:
0
8
8
0
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _