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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGF All Species: 31.52
Human Site: S149 Identified Species: 57.78
UniProt: Q07326 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07326 NP_002634.1 219 24890 S149 F S R N G V T S I W E N S L Q
Chimpanzee Pan troglodytes XP_001147889 219 24970 S149 F S R N G V T S I W E N S L Q
Rhesus Macaque Macaca mulatta XP_001113130 219 24899 S149 F S R N G V S S I W E N S L Q
Dog Lupus familis XP_531809 219 25180 S149 F S R N G V T S I W E N S L Q
Cat Felis silvestris
Mouse Mus musculus O09101 219 24806 S149 F S R N G V T S I W E N S L Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508401 403 43802 S204 F S K N G A S S I W D K S L Q
Chicken Gallus gallus
Frog Xenopus laevis NP_001088813 219 24617 S149 F S K D G A L S V W D H S L Q
Zebra Danio Brachydanio rerio NP_991208 219 24392 S149 F S R D G A M S V W D T S L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187877 166 17772 L107 F S L L G A W L G A F P I P L
Poplar Tree Populus trichocarpa XP_002303863 230 25414 E160 F A Q T K P N E P L E Y M I C
Maize Zea mays NP_001131399 218 23446 Y152 T P T D V E N Y M I S A P C H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06636 219 25243 S144 L W E T W L L S L H F A F L A
Red Bread Mold Neurospora crassa Q871U9 272 28468 R209 W A A V G G F R A P L D E T F
Conservation
Percent
Protein Identity: 100 99.5 97.2 92.6 N.A. 87.6 N.A. N.A. 28.5 N.A. 63 52.9 N.A. N.A. N.A. N.A. 34.7
Protein Similarity: 100 99.5 98.1 95.4 N.A. 92.2 N.A. N.A. 38.2 N.A. 81.2 75.8 N.A. N.A. N.A. N.A. 46.5
P-Site Identity: 100 100 93.3 100 N.A. 100 N.A. N.A. 66.6 N.A. 53.3 60 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 86.6 N.A. 86.6 80 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 25.6 29.6 N.A. N.A. 21.9 24.2
Protein Similarity: 44.7 49.3 N.A. N.A. 38.3 38.9
P-Site Identity: 13.3 0 N.A. N.A. 13.3 6.6
P-Site Similarity: 33.3 13.3 N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 0 0 31 0 0 8 8 0 16 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % C
% Asp: 0 0 0 24 0 0 0 0 0 0 24 8 0 0 0 % D
% Glu: 0 0 8 0 0 8 0 8 0 0 47 0 8 0 0 % E
% Phe: 77 0 0 0 0 0 8 0 0 0 16 0 8 0 8 % F
% Gly: 0 0 0 0 77 8 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 47 8 0 0 8 8 0 % I
% Lys: 0 0 16 0 8 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 8 0 8 8 0 8 16 8 8 8 8 0 0 70 8 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 8 0 0 % M
% Asn: 0 0 0 47 0 0 16 0 0 0 0 39 0 0 0 % N
% Pro: 0 8 0 0 0 8 0 0 8 8 0 8 8 8 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 62 % Q
% Arg: 0 0 47 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 70 0 0 0 0 16 70 0 0 8 0 62 0 0 % S
% Thr: 8 0 8 16 0 0 31 0 0 0 0 8 0 8 0 % T
% Val: 0 0 0 8 8 39 0 0 16 0 0 0 0 0 0 % V
% Trp: 8 8 0 0 8 0 8 0 0 62 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _