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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGF All Species: 21.21
Human Site: S71 Identified Species: 38.89
UniProt: Q07326 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07326 NP_002634.1 219 24890 S71 P N T S S K R S S L S H K V T
Chimpanzee Pan troglodytes XP_001147889 219 24970 S71 P N T S S K R S S L S H K V T
Rhesus Macaque Macaca mulatta XP_001113130 219 24899 S71 P N T S S K R S S L S H K V T
Dog Lupus familis XP_531809 219 25180 S71 P N A S S K R S S I S Y K V T
Cat Felis silvestris
Mouse Mus musculus O09101 219 24806 S71 P N V S S K R S S L S H K V T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508401 403 43802 G126 A Q G P A P N G G G S G Q V S
Chicken Gallus gallus
Frog Xenopus laevis NP_001088813 219 24617 S71 P N A S S K K S S L A N K F N
Zebra Danio Brachydanio rerio NP_991208 219 24392 N71 I S P P T K K N T L S Y K I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187877 166 17772 F33 L F F S S I A F H I V A V L Y
Poplar Tree Populus trichocarpa XP_002303863 230 25414 Q82 S R F R I D P Q Q C S Y L K A
Maize Zea mays NP_001131399 218 23446 G78 F F R A V A R G L I G L P V G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06636 219 25243 F69 Y V F V S S N F N T V K L L S
Red Bread Mold Neurospora crassa Q871U9 272 28468 A118 L P A A G E P A S K S N R K P
Conservation
Percent
Protein Identity: 100 99.5 97.2 92.6 N.A. 87.6 N.A. N.A. 28.5 N.A. 63 52.9 N.A. N.A. N.A. N.A. 34.7
Protein Similarity: 100 99.5 98.1 95.4 N.A. 92.2 N.A. N.A. 38.2 N.A. 81.2 75.8 N.A. N.A. N.A. N.A. 46.5
P-Site Identity: 100 100 100 80 N.A. 93.3 N.A. N.A. 13.3 N.A. 60 26.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 33.3 N.A. 80 80 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 25.6 29.6 N.A. N.A. 21.9 24.2
Protein Similarity: 44.7 49.3 N.A. N.A. 38.3 38.9
P-Site Identity: 6.6 13.3 N.A. N.A. 6.6 13.3
P-Site Similarity: 13.3 26.6 N.A. N.A. 26.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 24 16 8 8 8 8 0 0 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 16 24 0 0 0 0 16 0 0 0 0 0 8 0 % F
% Gly: 0 0 8 0 8 0 0 16 8 8 8 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 31 0 0 0 % H
% Ile: 8 0 0 0 8 8 0 0 0 24 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 54 16 0 0 8 0 8 54 16 0 % K
% Leu: 16 0 0 0 0 0 0 0 8 47 0 8 16 16 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 47 0 0 0 0 16 8 8 0 0 16 0 0 8 % N
% Pro: 47 8 8 16 0 8 16 0 0 0 0 0 8 0 8 % P
% Gln: 0 8 0 0 0 0 0 8 8 0 0 0 8 0 0 % Q
% Arg: 0 8 8 8 0 0 47 0 0 0 0 0 8 0 0 % R
% Ser: 8 8 0 54 62 8 0 47 54 0 70 0 0 0 24 % S
% Thr: 0 0 24 0 8 0 0 0 8 8 0 0 0 0 39 % T
% Val: 0 8 8 8 8 0 0 0 0 0 16 0 8 54 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 24 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _