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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGF
All Species:
25.15
Human Site:
S74
Identified Species:
46.11
UniProt:
Q07326
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07326
NP_002634.1
219
24890
S74
S
S
K
R
S
S
L
S
H
K
V
T
G
F
L
Chimpanzee
Pan troglodytes
XP_001147889
219
24970
S74
S
S
K
R
S
S
L
S
H
K
V
T
R
F
L
Rhesus Macaque
Macaca mulatta
XP_001113130
219
24899
S74
S
S
K
R
S
S
L
S
H
K
V
T
R
F
L
Dog
Lupus familis
XP_531809
219
25180
S74
S
S
K
R
S
S
I
S
Y
K
V
T
R
F
L
Cat
Felis silvestris
Mouse
Mus musculus
O09101
219
24806
S74
S
S
K
R
S
S
L
S
H
K
V
T
R
A
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508401
403
43802
S129
P
A
P
N
G
G
G
S
G
Q
V
S
R
F
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088813
219
24617
A74
S
S
K
K
S
S
L
A
N
K
F
N
K
L
T
Zebra Danio
Brachydanio rerio
NP_991208
219
24392
S74
P
T
K
K
N
T
L
S
Y
K
I
S
R
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187877
166
17772
V36
S
S
I
A
F
H
I
V
A
V
L
Y
G
A
P
Poplar Tree
Populus trichocarpa
XP_002303863
230
25414
S85
R
I
D
P
Q
Q
C
S
Y
L
K
A
V
V
R
Maize
Zea mays
NP_001131399
218
23446
G81
A
V
A
R
G
L
I
G
L
P
V
G
A
F
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06636
219
25243
V72
V
S
S
N
F
N
T
V
K
L
L
S
F
L
I
Red Bread Mold
Neurospora crassa
Q871U9
272
28468
S121
A
G
E
P
A
S
K
S
N
R
K
P
R
P
G
Conservation
Percent
Protein Identity:
100
99.5
97.2
92.6
N.A.
87.6
N.A.
N.A.
28.5
N.A.
63
52.9
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
99.5
98.1
95.4
N.A.
92.2
N.A.
N.A.
38.2
N.A.
81.2
75.8
N.A.
N.A.
N.A.
N.A.
46.5
P-Site Identity:
100
93.3
93.3
80
N.A.
86.6
N.A.
N.A.
26.6
N.A.
46.6
33.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
N.A.
N.A.
46.6
N.A.
66.6
80
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
25.6
29.6
N.A.
N.A.
21.9
24.2
Protein Similarity:
44.7
49.3
N.A.
N.A.
38.3
38.9
P-Site Identity:
6.6
26.6
N.A.
N.A.
6.6
13.3
P-Site Similarity:
13.3
40
N.A.
N.A.
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
8
8
0
0
8
8
0
0
8
8
16
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
16
0
0
0
0
0
8
0
8
54
8
% F
% Gly:
0
8
0
0
16
8
8
8
8
0
0
8
16
0
8
% G
% His:
0
0
0
0
0
8
0
0
31
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
24
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
54
16
0
0
8
0
8
54
16
0
8
0
0
% K
% Leu:
0
0
0
0
0
8
47
0
8
16
16
0
0
16
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
8
8
0
0
16
0
0
8
0
0
0
% N
% Pro:
16
0
8
16
0
0
0
0
0
8
0
8
0
8
8
% P
% Gln:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
0
47
0
0
0
0
0
8
0
0
54
0
8
% R
% Ser:
54
62
8
0
47
54
0
70
0
0
0
24
0
0
0
% S
% Thr:
0
8
0
0
0
8
8
0
0
0
0
39
0
0
8
% T
% Val:
8
8
0
0
0
0
0
16
0
8
54
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
24
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _