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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGF All Species: 8.79
Human Site: T66 Identified Species: 16.11
UniProt: Q07326 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07326 NP_002634.1 219 24890 T66 Y L V V K P N T S S K R S S L
Chimpanzee Pan troglodytes XP_001147889 219 24970 T66 Y L V V K P N T S S K R S S L
Rhesus Macaque Macaca mulatta XP_001113130 219 24899 T66 Y L A V K P N T S S K R S S L
Dog Lupus familis XP_531809 219 25180 A66 Y L I V K P N A S S K R S S I
Cat Felis silvestris
Mouse Mus musculus O09101 219 24806 V66 Y L V V K P N V S S K R S S L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508401 403 43802 G121 V P S T S A Q G P A P N G G G
Chicken Gallus gallus
Frog Xenopus laevis NP_001088813 219 24617 A66 L L T L K P N A S S K K S S L
Zebra Danio Brachydanio rerio NP_991208 219 24392 P66 F W L L G I S P P T K K N T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187877 166 17772 F28 K Y G L L L F F S S I A F H I
Poplar Tree Populus trichocarpa XP_002303863 230 25414 F77 V I L I Y S R F R I D P Q Q C
Maize Zea mays NP_001131399 218 23446 R73 A K S C S F F R A V A R G L I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06636 219 25243 F64 A L L Y Y Y V F V S S N F N T
Red Bread Mold Neurospora crassa Q871U9 272 28468 A113 Y A L L C L P A A G E P A S K
Conservation
Percent
Protein Identity: 100 99.5 97.2 92.6 N.A. 87.6 N.A. N.A. 28.5 N.A. 63 52.9 N.A. N.A. N.A. N.A. 34.7
Protein Similarity: 100 99.5 98.1 95.4 N.A. 92.2 N.A. N.A. 38.2 N.A. 81.2 75.8 N.A. N.A. N.A. N.A. 46.5
P-Site Identity: 100 100 93.3 80 N.A. 93.3 N.A. N.A. 0 N.A. 66.6 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 N.A. N.A. 6.6 N.A. 80 66.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 25.6 29.6 N.A. N.A. 21.9 24.2
Protein Similarity: 44.7 49.3 N.A. N.A. 38.3 38.9
P-Site Identity: 0 6.6 N.A. N.A. 13.3 13.3
P-Site Similarity: 20 20 N.A. N.A. 26.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 8 0 0 8 0 24 16 8 8 8 8 0 0 % A
% Cys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 8 0 0 0 0 8 16 24 0 0 0 0 16 0 0 % F
% Gly: 0 0 8 0 8 0 0 8 0 8 0 0 16 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 8 8 0 8 0 0 0 8 8 0 0 0 24 % I
% Lys: 8 8 0 0 47 0 0 0 0 0 54 16 0 0 8 % K
% Leu: 8 54 31 31 8 16 0 0 0 0 0 0 0 8 47 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 47 0 0 0 0 16 8 8 0 % N
% Pro: 0 8 0 0 0 47 8 8 16 0 8 16 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 8 8 0 % Q
% Arg: 0 0 0 0 0 0 8 8 8 0 0 47 0 0 0 % R
% Ser: 0 0 16 0 16 8 8 0 54 62 8 0 47 54 0 % S
% Thr: 0 0 8 8 0 0 0 24 0 8 0 0 0 8 8 % T
% Val: 16 0 24 39 0 0 8 8 8 8 0 0 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 47 8 0 8 16 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _