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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAG1
All Species:
17.58
Human Site:
S222
Identified Species:
32.22
UniProt:
Q07617
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07617
NP_003105.2
926
103639
S222
K
G
N
E
A
F
N
S
G
D
Y
E
E
A
V
Chimpanzee
Pan troglodytes
XP_001151756
925
103559
S222
K
G
N
E
A
F
N
S
G
D
Y
E
E
A
V
Rhesus Macaque
Macaca mulatta
XP_001097243
934
104557
S222
K
G
N
E
A
F
N
S
G
D
Y
E
E
A
V
Dog
Lupus familis
XP_848730
421
47825
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZX8
901
100651
S226
K
G
N
E
A
F
Y
S
G
D
Y
E
E
A
V
Rat
Rattus norvegicus
Q5U2X2
893
100597
S226
K
G
N
E
A
F
Y
S
G
D
Y
E
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506694
365
42180
Chicken
Gallus gallus
Q5ZKQ3
665
75976
K33
R
E
L
E
S
W
E
K
D
I
K
E
V
D
S
Frog
Xenopus laevis
Q6NU95
660
75087
E27
D
L
Q
D
F
M
R
E
M
E
S
W
E
K
D
Zebra Danio
Brachydanio rerio
NP_001082875
386
42425
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651514
469
53806
Honey Bee
Apis mellifera
XP_394942
579
66433
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15705
589
66247
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
34.8
N.A.
68.9
67.7
N.A.
29.9
24.1
23.6
24.8
N.A.
21.8
20.7
N.A.
N.A.
Protein Similarity:
100
99.4
96.5
39.8
N.A.
79.3
77.7
N.A.
34.5
39.8
38.9
31.4
N.A.
35.3
37
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
0
13.3
6.6
0
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
93.3
93.3
N.A.
0
33.3
20
0
N.A.
0
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
39
0
0
0
0
0
0
0
0
39
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
8
39
0
0
0
8
8
% D
% Glu:
0
8
0
47
0
0
8
8
0
8
0
47
47
0
0
% E
% Phe:
0
0
0
0
8
39
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
39
0
0
0
0
0
0
39
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
39
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% K
% Leu:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
39
0
0
0
24
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
39
0
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
39
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
0
0
0
39
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _