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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPAG1 All Species: 20.61
Human Site: T887 Identified Species: 37.78
UniProt: Q07617 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07617 NP_003105.2 926 103639 T887 E R F K M M L T L I S K G Q K
Chimpanzee Pan troglodytes XP_001151756 925 103559 T886 E R F K M M L T L I S Q G Q K
Rhesus Macaque Macaca mulatta XP_001097243 934 104557 T895 E R F K M M L T L I S K G Q E
Dog Lupus familis XP_848730 421 47825 G383 D E G G K D S G R T H K D G S
Cat Felis silvestris
Mouse Mus musculus Q80ZX8 901 100651 T862 E R F K T M L T L I N K G Q K
Rat Rattus norvegicus Q5U2X2 893 100597 A854 E R F E M M L A L T S K D Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506694 365 42180 S327 V E K E L K D S E P A S G I Q
Chicken Gallus gallus Q5ZKQ3 665 75976 M627 K R F D M A V M F M S G S E K
Frog Xenopus laevis Q6NU95 660 75087 A622 E L K R F D M A V M F L S E S
Zebra Danio Brachydanio rerio NP_001082875 386 42425 A348 G L K D Y L S A S T D L Q E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651514 469 53806 S431 L G N K M Q A S K G G A P K K
Honey Bee Apis mellifera XP_394942 579 66433 S541 I S Q M K R F S I I N M F M S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P15705 589 66247 S551 M Q D P V M Q S I L Q Q A Q Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95 34.8 N.A. 68.9 67.7 N.A. 29.9 24.1 23.6 24.8 N.A. 21.8 20.7 N.A. N.A.
Protein Similarity: 100 99.4 96.5 39.8 N.A. 79.3 77.7 N.A. 34.5 39.8 38.9 31.4 N.A. 35.3 37 N.A. N.A.
P-Site Identity: 100 93.3 93.3 6.6 N.A. 86.6 73.3 N.A. 6.6 33.3 6.6 0 N.A. 20 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 93.3 80 N.A. 40 60 40 13.3 N.A. 33.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 8 24 0 0 8 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 16 0 16 8 0 0 0 8 0 16 0 0 % D
% Glu: 47 16 0 16 0 0 0 0 8 0 0 0 0 24 8 % E
% Phe: 0 0 47 0 8 0 8 0 8 0 8 0 8 0 0 % F
% Gly: 8 8 8 8 0 0 0 8 0 8 8 8 39 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 16 39 0 0 0 8 0 % I
% Lys: 8 0 24 39 16 8 0 0 8 0 0 39 0 8 47 % K
% Leu: 8 16 0 0 8 8 39 0 39 8 0 16 0 0 0 % L
% Met: 8 0 0 8 47 47 8 8 0 16 0 8 0 8 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 16 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 8 0 0 8 0 0 % P
% Gln: 0 8 8 0 0 8 8 0 0 0 8 16 8 47 16 % Q
% Arg: 0 47 0 8 0 8 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 0 16 31 8 0 39 8 16 0 24 % S
% Thr: 0 0 0 0 8 0 0 31 0 24 0 0 0 0 0 % T
% Val: 8 0 0 0 8 0 8 0 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _