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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC3A1
All Species:
27.88
Human Site:
Y461
Identified Species:
51.11
UniProt:
Q07837
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07837
NP_000332.2
685
78852
Y461
T
S
R
L
G
N
Q
Y
V
N
V
M
N
M
L
Chimpanzee
Pan troglodytes
XP_515443
685
79014
Y461
T
S
R
L
G
N
Q
Y
V
N
V
M
N
M
L
Rhesus Macaque
Macaca mulatta
XP_001112327
681
78437
Y457
T
S
R
L
G
N
E
Y
V
N
V
M
N
M
L
Dog
Lupus familis
XP_855564
700
79914
Y476
T
S
R
F
G
E
E
Y
V
N
I
M
N
M
L
Cat
Felis silvestris
Mouse
Mus musculus
P10852
526
58318
F316
T
E
S
L
V
T
R
F
L
N
A
T
G
S
Q
Rat
Rattus norvegicus
Q64319
683
78488
Y458
T
S
R
V
G
S
E
Y
V
N
A
M
N
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521558
430
48891
T220
L
V
L
T
L
P
G
T
P
I
T
Y
Y
G
E
Chicken
Gallus gallus
XP_426125
688
78248
Y461
S
S
R
F
G
S
E
Y
V
R
V
I
N
M
L
Frog
Xenopus laevis
NP_001089867
693
79666
Y466
A
S
R
V
G
R
Q
Y
V
N
V
M
N
M
L
Zebra Danio
Brachydanio rerio
XP_685969
672
78047
Y449
G
S
S
A
G
K
E
Y
V
R
A
L
N
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07190
577
66367
V367
G
N
H
D
N
K
R
V
A
S
R
F
G
V
Q
Honey Bee
Apis mellifera
Q17058
567
65546
G357
L
R
L
V
S
R
F
G
E
E
K
A
R
M
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53341
584
68076
L374
I
S
G
K
L
L
T
L
L
E
C
S
L
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
90.6
78.1
N.A.
23.5
79.5
N.A.
37.6
60.4
57.5
52.1
N.A.
32.4
31
N.A.
N.A.
Protein Similarity:
100
98.9
93.4
86.7
N.A.
40.8
88.6
N.A.
48.1
77.9
73.8
70.3
N.A.
50
49.9
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
20
73.3
N.A.
0
60
80
46.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
40
93.3
N.A.
0
86.6
86.6
60
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
8
0
24
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
39
0
8
16
0
0
0
0
8
% E
% Phe:
0
0
0
16
0
0
8
8
0
0
0
8
0
0
0
% F
% Gly:
16
0
8
0
62
0
8
8
0
0
0
0
16
8
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
8
8
0
0
8
% I
% Lys:
0
0
0
8
0
16
0
0
0
0
8
0
0
0
0
% K
% Leu:
16
0
16
31
16
8
0
8
16
0
0
8
8
0
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
47
0
70
0
% M
% Asn:
0
8
0
0
8
24
0
0
0
54
0
0
62
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
16
% Q
% Arg:
0
8
54
0
0
16
16
0
0
16
8
0
8
0
0
% R
% Ser:
8
70
16
0
8
16
0
0
0
8
0
8
0
8
0
% S
% Thr:
47
0
0
8
0
8
8
8
0
0
8
8
0
8
0
% T
% Val:
0
8
0
24
8
0
0
8
62
0
39
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _