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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC3A1
All Species:
16.97
Human Site:
Y579
Identified Species:
31.11
UniProt:
Q07837
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07837
NP_000332.2
685
78852
Y579
H
L
R
N
D
S
H
Y
V
V
Y
T
R
E
L
Chimpanzee
Pan troglodytes
XP_515443
685
79014
Y579
H
L
R
N
D
S
H
Y
V
V
Y
T
R
E
L
Rhesus Macaque
Macaca mulatta
XP_001112327
681
78437
Y575
H
L
R
N
D
S
H
Y
V
V
Y
T
R
E
L
Dog
Lupus familis
XP_855564
700
79914
S594
Y
L
R
N
D
S
H
S
V
V
Y
A
R
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P10852
526
58318
E426
L
S
D
L
R
G
K
E
R
S
L
L
H
G
D
Rat
Rattus norvegicus
Q64319
683
78488
S576
L
L
R
D
D
N
H
S
V
V
Y
T
R
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521558
430
48891
E330
N
L
V
V
Y
S
R
E
L
D
G
L
D
R
V
Chicken
Gallus gallus
XP_426125
688
78248
V582
S
I
W
N
D
S
D
V
F
V
Y
V
R
E
L
Frog
Xenopus laevis
NP_001089867
693
79666
V587
Y
T
W
S
D
N
N
V
F
A
Y
V
R
E
L
Zebra Danio
Brachydanio rerio
XP_685969
672
78047
V571
Y
V
W
N
D
V
N
V
F
A
Y
L
R
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07190
577
66367
I477
A
P
R
S
H
L
Q
I
F
K
K
L
V
R
V
Honey Bee
Apis mellifera
Q17058
567
65546
A467
F
N
M
F
K
K
F
A
S
L
K
K
S
P
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53341
584
68076
D484
N
V
E
Q
E
S
R
D
D
D
S
V
L
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
90.6
78.1
N.A.
23.5
79.5
N.A.
37.6
60.4
57.5
52.1
N.A.
32.4
31
N.A.
N.A.
Protein Similarity:
100
98.9
93.4
86.7
N.A.
40.8
88.6
N.A.
48.1
77.9
73.8
70.3
N.A.
50
49.9
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
0
73.3
N.A.
13.3
53.3
33.3
40
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
0
86.6
N.A.
33.3
60
60
60
N.A.
20
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
16
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
62
0
8
8
8
16
0
0
8
0
8
% D
% Glu:
0
0
8
0
8
0
0
16
0
0
0
0
0
62
0
% E
% Phe:
8
0
0
8
0
0
8
0
31
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
0
% G
% His:
24
0
0
0
8
0
39
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
8
8
0
0
8
16
8
0
0
0
% K
% Leu:
16
47
0
8
0
8
0
0
8
8
8
31
8
0
62
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
8
0
47
0
16
16
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
47
0
8
0
16
0
8
0
0
0
62
16
0
% R
% Ser:
8
8
0
16
0
54
0
16
8
8
8
0
8
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
31
0
0
0
% T
% Val:
0
16
8
8
0
8
0
24
39
47
0
24
8
0
16
% V
% Trp:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
0
0
0
8
0
0
24
0
0
62
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _