KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLC1
All Species:
14.85
Human Site:
Y532
Identified Species:
36.3
UniProt:
Q07866
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07866
NP_001123579.1
573
65310
Y532
L
N
V
D
V
V
K
Y
E
S
G
P
D
G
G
Chimpanzee
Pan troglodytes
XP_001139827
637
71958
Y532
L
N
V
D
V
V
K
Y
E
S
G
P
D
G
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868683
551
62638
R519
D
P
E
N
V
E
K
R
R
S
R
E
S
L
T
Cat
Felis silvestris
Mouse
Mus musculus
O88447
541
61432
V508
H
K
Q
R
V
A
E
V
L
N
D
P
E
S
M
Rat
Rattus norvegicus
P37285
560
63726
R522
N
V
E
K
R
R
S
R
E
S
L
N
V
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508875
610
68899
Y532
L
N
V
D
V
V
K
Y
E
S
G
P
D
G
G
Chicken
Gallus gallus
XP_421389
637
72024
Y532
L
N
V
D
V
V
K
Y
E
S
G
P
D
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46824
508
58026
S466
L
E
D
C
A
M
R
S
K
K
E
A
Y
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46822
540
60206
Q505
G
G
I
D
E
M
S
Q
S
M
M
A
S
T
I
Sea Urchin
Strong. purpuratus
Q05090
686
76498
G548
S
S
G
T
P
R
H
G
S
T
E
S
V
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
N.A.
95.6
N.A.
90.4
94.7
N.A.
89.1
86.5
N.A.
N.A.
N.A.
63.3
N.A.
59.1
60.2
Protein Similarity:
100
88.8
N.A.
95.9
N.A.
92.6
97
N.A.
91.1
88.5
N.A.
N.A.
N.A.
76
N.A.
72.4
69.2
P-Site Identity:
100
100
N.A.
20
N.A.
13.3
13.3
N.A.
100
100
N.A.
N.A.
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
N.A.
26.6
N.A.
33.3
13.3
N.A.
100
100
N.A.
N.A.
N.A.
26.6
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
0
20
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
50
0
0
0
0
0
0
10
0
40
20
0
% D
% Glu:
0
10
20
0
10
10
10
0
50
0
20
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
0
0
0
10
0
0
40
0
0
40
40
% G
% His:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
10
0
10
0
0
50
0
10
10
0
0
0
0
0
% K
% Leu:
50
0
0
0
0
0
0
0
10
0
10
0
0
10
10
% L
% Met:
0
0
0
0
0
20
0
0
0
10
10
0
0
0
10
% M
% Asn:
10
40
0
10
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
0
0
0
0
50
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
20
10
20
10
0
10
0
0
0
0
% R
% Ser:
10
10
0
0
0
0
20
10
20
60
0
10
20
20
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
10
0
0
0
10
10
% T
% Val:
0
10
40
0
60
40
0
10
0
0
0
0
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _